Protein Alignment EndoA and EndoA

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_061497931.1
• Gene: EndoA / 1278459
• VectorBaseID: AGAMI1_001867
• Length: 573
• Species: Anopheles gambiae
• Alignment Length: 575
• Identity: 298/575 - (51%)
• Similarity: 333/575 - (57%)
• Gaps: 211/575 - (36%)

  Fly     1 MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTAR 65
            ||||||||||||||||:|||||||||||||:||||||||||||||||||||.||||:||||||||
Mosquito     1 MAFAGLKKQINKANQYVTEKMGGAEGTKLDLDFMEMERKTDVTVELVEELQAKTKEYLQPNPTAR 65

  Fly    66 AKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKY 130
            ||||||||||||||||||||||||||:||:|||||||||||| |:||.||||.|::|||||||||
Mosquito    66 AKMAAVKGISKLSGQAKSNTYPQPEGILADCMLTYGKKLGED-SIFASALVEMGDSLKQMADVKY 129

  Fly   131 SLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK-----DDEIRGAEDKFG 190
            |||||||||||||||.:|||||||||||||||||||||||||:|||||     |||||.||:||.
Mosquito   130 SLDDNIKQNFLEPLHQLQTKDLKEVMHHRKKLQGRRLDFDCKKRRQAKGSQITDDEIRSAEEKFA 194

  Fly   191 ESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFV 255
            ||||||||||:||||||.|.|||||||||.:.|:||||:::|:.|.|||.|||.||.:||::|||
Mosquito   195 ESLQLAQVGMYNLLENDVEQVSQLVTFAEGMLDYHSQCSEILKVLVETLNEKREEAAARPKSEFV 259

  Fly   256 PKTLLDLNLD------------------------------------------------------- 265
            ||||.|||::
Mosquito   260 PKTLADLNIEMLGSQDGMNGGPHFLNPNRLNNSHHHMYSSQQNLSNNKTYSSNHNNNSSHFNRNR 324

  Fly   266 --------------------GGGGGLNED------------------------------------ 274
                                ||.||...|
Mosquito   325 LYGSQQSLSSTRSGGTSSAFGGVGGRAGDTSGIDSISSTDGSDMRPPSYGSSVDSWLNAWDQPNN 389

  Fly   275 ----------------------------------------------------------------- 274
                                                                             
Mosquito   390 GGYAGNGGIGAGSKPGKSTTTSNSGANIRNNNTNSYSSMYSTATTNSTAMFANNNNNNNNSKSIF 454

  Fly   275 ------GTPSHISS---------------------SASPLPSPMRSPAKSMAVTPQRQQQPCCQA 312
                  |:.||:||                     :||||||||||||::  ..|.:..||||.|
Mosquito   455 SDPWSGGSSSHLSSPVNKPTHLELLGNGQAQARSTNASPLPSPMRSPART--PMPTKPTQPCCTA 517

  Fly   313 LYDFEPENPGELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQVPLPN 367
            ||||||||||||.|||||:|||:.|||:|||||::|||.||||||||||.||||:
Mosquito   518 LYDFEPENPGELGFKENDVITLIQRVDENWFEGSLNGRNGYFPQSYVQVTVPLPS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	188/225 (84%)
		SH3_Endophilin_A	312..361	CDD:212737	40/48 (83%)
EndoA	XP_061497931.1	None