DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh2 and Opn1mw

DIOPT Version :9

Sequence 1:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_446000.1	Gene:	Opn1mw / 89810	RGDID:	620978	Length:	359	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	93/344 - (27%)
Similarity:	153/344 - (44%)	Gaps:	43/344 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCM 106
            :.|.|         :..:...:.:.::|.|...||:|:......|.||.|.|.:::|||.:|...
  Rat    42 IAPRW---------VYHLTSTWMILVVIASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAE 97

  Fly   107 MASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIK 171
            ....|.:.::|..|..:|||...|.|.....||.|...:||:.:|:::|:.|:.|.........|
  Rat    98 TIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAK 162

  Fly   172 TSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNP--RSYLITYSLFVYYTPL 234
            .:.:.|:|.|:.|..||..|:.|||.|.|.|..|:|..|..:....|  :||::...:.....||
  Rat   163 LATVGIVFSWVWAAVWTAPPIFGWSRYWPYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPL 227

  Fly   235 FLI--CY-SYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAW 296
            .:|  || ..|..|.|||..:|               .||...| ||.::.::.:..:..:.:.|
  Rat   228 SIIVLCYLQVWLAIRAVAKQQK---------------ESESTQK-AEKEVTRMVVVMVFAYCLCW 276

  Fly   297 TPYLVICYFGLFKID----GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVFG 357
            .||   .:|..|...    ...||.....:.|||::.:||||:|...:.::|     .|.:.:||
  Rat   277 GPY---TFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFR-----NCILQLFG 333

  Fly   358 -NTDEPKPDAPASDTETTS 375
             ..|:....:..|.||.:|
  Rat   334 KKVDDSSELSSTSKTEVSS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	53/171 (31%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	79/270 (29%)
Opn1mw	NP_446000.1	Required for 11-cis-retinal regeneration. /evidence=ECO:0000250\|UniProtKB:P04001	12..38
Opn1mw	NP_446000.1	7tm_1	66..317	CDD:278431	79/269 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910