DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh2 and Lkr

DIOPT Version :9

Sequence 1:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_647968.3	Gene:	Lkr / 38622	FlyBaseID:	FBgn0035610	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	72/329 - (21%)
Similarity:	140/329 - (42%)	Gaps:	62/329 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 ILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSD-----FCMMASQSPVMIINF 118
            :|.:|...|.|::..||.:|:::...|:.:||..|:.:.||||:|     ||:     |......
  Fly    37 LLSIFYGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLFCI-----PFQFQAA 96

  Fly   119 YYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILF--IW 181
            ..::|.|....|.......:|...||::::..||.||:..|:..:...|...   :.|.:.  ||
  Fly    97 LLQSWNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKF---VSKFIIGGIW 158

  Fly   182 MMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMW--NPRSYLIT------------------YS 226
            |:|:.:.|...|            |..::.:|..:  |..:|.:|                  |:
  Fly   159 MLALLFAVPFAI------------AFRVEELTERFRENNETYNVTRPFCMNKNLSDDQLQSFRYT 211

  Fly   227 L-FVYYTPLFLICYSYWFIIAAVAA-HEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTI 289
            | ||.|...|.: .|:.:|..||.. ..:|........::..|::.:        |:.|:.:..:
  Fly   212 LVFVQYLVPFCV-ISFVYIQMAVRLWGTRAPGNAQDSRDITLLKNKK--------KVIKMLIIVV 267

  Fly   290 SLWFMAWTPYLV--ICYFGLFKIDGLTPLTTIWGAT--FAKTSAVYNPIVYGISHPKYRIVLKEK 350
            .::.:.|.|..:  |.|..:.:|:....::.:|...  .|.:::.|||.:|||.:.|::....::
  Fly   268 IIFGLCWLPLQLYNILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKR 332

  Fly   351 CPMC 354
            ...|
  Fly   333 FAAC 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	47/197 (24%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	63/294 (21%)
Lkr	NP_647968.3	7tm_4	46..329	CDD:304433	68/311 (22%)
		7tm_1	52..318	CDD:278431	63/294 (21%)
		PHA03216	467..>519	CDD:177558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45695
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010