DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh2 and Opn5

DIOPT Version :9

Sequence 1:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_038939470.1	Gene:	Opn5 / 316259	RGDID:	727869	Length:	533	Species:	Rattus norvegicus

Alignment Length:	346	Identity:	95/346 - (27%)
Similarity:	150/346 - (43%)	Gaps:	50/346 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPDMAHLVNPYWSRFAPMDPMMSK-------ILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPA 92
            ||....|  |::.|  ..||..||       :.|.:...|.|:|..|||.|:|:....|....||
  Rat     8 LPQDERL--PHYLR--DEDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPA 68

  Fly    93 NLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYN 157
            .::.:|||..|..:.....|..||:.:...||.|...|..|...|..|||.|:.:|..::.|||.
  Rat    69 EIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWFGCRWYGWAGFFFGCGSLITMTAVSLDRYL 133

  Fly   158 VIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRS-- 220
            .|.....|..:..|.:.:.:..||..|.|||.|||:|...|.||...|:|::|:    |..::
  Rat   134 KICYLSYGVWLKRKHAYICLAVIWAYASFWTTMPLVGLGDYAPEPFGTSCTLDW----WLAQASG 194

  Fly   221 ----YLITYSLFVYYTPLFLICYSYWFIIAAV------AAHEKAMREQAKKMNVKSLRSSEDCDK 275
                ::::...|....|..:|.:||..|||.|      .||..:....:..:.||..:.....|.
  Rat   195 GGQVFILSILFFCLLLPTAVIVFSYAKIIAKVKSSSKEVAHFDSRIHSSHVLEVKLTKGLVRADS 259

  Fly   276 SAE----------------------GKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGLTPL-T 317
            |.|                      .:::.||:...:.:.:||.||.|:..:..|......|: .
  Rat   260 SPESLPRSVFSTAEPINCHVLSISHSRVSTVAMLICAGFLIAWIPYAVVSVWSAFGRPNSIPIQL 324

  Fly   318 TIWGATFAKTSAVYNPIVYGI 338
            ::.....||::|:||||:|.:
  Rat   325 SVVPTLLAKSAAMYNPIIYQV 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	54/175 (31%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	81/296 (27%)
Opn5	XP_038939470.1	7tmA_Opsin5_neuropsin	34..353	CDD:320202	86/316 (27%)
		TM helix 1	36..60	CDD:320202	9/23 (39%)
		TM helix 2	69..91	CDD:320202	5/21 (24%)
		TM helix 3	107..129	CDD:320202	7/21 (33%)
		TM helix 4	151..167	CDD:320202	6/15 (40%)
		TM helix 5	197..220	CDD:320202	4/22 (18%)
		TM helix 6	251..310	CDD:320202	10/58 (17%)
		TM helix 7	322..347	CDD:320202	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910