Protein Alignment Rh2 and OPN5

DIOPT Version :10

• Sequence 1: NP_524398.1
• Gene: Rh2 / 42261
• FlyBaseID: FBgn0003248
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: XP_016865905.1
• Gene: OPN5 / 221391
• HGNCID: 19992
• Length: 408
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 95/323 - (29%)
• Similarity: 151/323 - (46%)
• Gaps: 31/323 - (9%)

  Fly    35 LPDMAHLVNPYWSRFAPMDPMMSK-------ILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPA 92
            ||....|  |::.|..  ||..||       :.|.:...|.|:|..|||.|:|:....|....||
Human     8 LPQDERL--PHYLRDG--DPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPA 68

  Fly    93 NLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYN 157
            .::.:|||..|..:.....|..||:.:...||.|.:.|..|...|..|||.|:.:|..::.|||.
Human    69 EIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYL 133

  Fly   158 VIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRS-- 220
            .|.....|..:..|.:.:.:..||..|.|||.|||:|...||||...|:|::|:    |..::
Human   134 KICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDW----WLAQASV 194

  Fly   221 ----YLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKL 281
                :::....|....|..:|.:||..|||.|.:..|.:.....:::...:         .|.||
Human   195 GGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHV---------LEMKL 250

  Fly   282 AKVALTTISLWFMAWTPYLVICYFGLF-KIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPKY 343
            .|||:...:.:.:||.||.|:..:..| :.|.:....::.....||::|:||||:|.:...|:
Human   251 TKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tmA_photoreceptors_insect	59..347	CDD:320207	86/292 (29%)
		TM helix 1	59..85	CDD:320207	9/25 (36%)
		TM helix 2	92..118	CDD:320207	8/25 (32%)
		TM helix 3	130..160	CDD:320207	11/29 (38%)
		TM helix 4	171..191	CDD:320207	7/19 (37%)
		TM helix 5	218..247	CDD:320207	7/34 (21%)
		TM helix 6	276..306	CDD:320207	11/29 (38%)
		TM helix 7	315..340	CDD:320207	8/24 (33%)
OPN5	XP_016865905.1	7tmA_Opsin5_neuropsin	34..316	CDD:320202	86/293 (29%)
		TM helix 1	35..61	CDD:320202	9/25 (36%)
		TM helix 2	68..95	CDD:320202	8/26 (31%)
		TM helix 3	106..136	CDD:320202	11/29 (38%)
		TM helix 4	149..167	CDD:320202	6/17 (35%)
		TM helix 5	196..226	CDD:320202	8/29 (28%)
		TM helix 6	245..275	CDD:320202	11/38 (29%)
		TM helix 7	285..310	CDD:320202	8/24 (33%)