DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh2 and Opn4

DIOPT Version :9

Sequence 1:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_620215.1	Gene:	Opn4 / 192223	RGDID:	621701	Length:	474	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	126/363 - (34%)
Similarity:	182/363 - (50%)	Gaps:	50/363 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNL 99
            :||.||..                 ||...|.:.:....||..|:|.|...:.||||||:|::||
  Rat    65 VPDHAHYT-----------------LGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINL 112

  Fly   100 AFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGIN 164
            |.|||.|..:|:||...:..|:.|:.|...|..||.||::||.||:.::..||.|||.||.:.:.
  Rat   113 AVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLA 177

  Fly   165 GTPMTIK-TSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLF 228
            ...|..| .:.:.:|.:|:.|:.|::.|..|||||||||.||:||.||:|.....|:|.:....|
  Rat   178 TIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCF 242

  Fly   229 VYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKS-----------AEGKLA 282
            |::.||.:|.:.|.||.       :|:||..        |:.|.|.:|           :|.|:|
  Rat   243 VFFLPLLIIIFCYIFIF-------RAIRETG--------RACEGCGESPLRRRQWQRLQSEWKMA 292

  Fly   283 KVALTTISLWFMAWTPYLVICYFGLFKIDG-LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIV 346
            ||||..|.|:.::|.||..:...|...... |||..:...|..||.||::|||:|.|:|||||..
  Rat   293 KVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAA 357

  Fly   347 LKEKCP-----MCVFGNTDEPKPDAPASDTETTSEADS 379
            :.:..|     :.|.|....|.....::...|.|...|
  Rat   358 IAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	70/170 (41%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	105/274 (38%)
Opn4	NP_620215.1	7tm_4	78..>245	CDD:304433	69/166 (42%)
		7tm_1	87..347	CDD:278431	105/274 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..474
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349214
Domainoid	1	1.000	186	1.000	Domainoid score	I3256
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69152
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3580
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D389088at33208
OrthoFinder	1	1.000	-	-		FOG0001799
OrthoInspector	1	1.000	-	-		otm44480
orthoMCL	1	0.900	-	-		OOG6_104608
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800