DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rh2 and npr-4

DIOPT Version :9

Sequence 1:NP_524398.1 Gene:Rh2 / 42261 FlyBaseID:FBgn0003248 Length:381 Species:Drosophila melanogaster
Sequence 2:NP_001300304.1 Gene:npr-4 / 182684 WormBaseID:WBGene00007635 Length:490 Species:Caenorhabditis elegans


Alignment Length:373 Identity:76/373 - (20%)
Similarity:134/373 - (35%) Gaps:92/373 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 NGSVLDNVLPDMAHLVNPYW-------SRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGG 84
            |||       |..:|.:..|       ||:..|  ::...|.|..:|..||   ||..|:.....
 Worm    24 NGS-------DCLNLNSELWLYREDLSSRWYIM--LVFAFLYLIIIAAGII---GNSCVILAITR 76

  Fly    85 TKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMC 149
            .|||:|..||.:|:|:.||..:..:.:.:..|..:.:.|:.|...|.|......:..|.|.:::.
 Worm    77 NKSLQTVPNLFILSLSCSDIVVCCTSATITPITAFKKEWIFGEALCRIAPFIAGISLCFSTFTLT 141

  Fly   150 MIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTR 214
            .|:.||| ::::.....|:|...::..|..|...|.  |:...|.:...:.|.. ..|. .|.|.
 Worm   142 AISIDRY-ILIRFPMRKPITHYQAVGVIAIICAFAA--TITSPIMFKQKLGEFE-NFCG-QYCTE 201

  Fly   215 MWNP-----RSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCD 274
            .|..     :.|...........||.:|..||..|...:.  :..:.:.|||...    .:.:.:
 Worm   202 NWGANESQRKIYGAALMFLQLVIPLTIIIISYTAISLKIG--QSMILKGAKKQKT----DNWEME 260

  Fly   275 KSAEGKLA--------KVALTTISLWFMAWTPYLVICYFGLFKIDGLTPLTTIWGATF------- 324
            .|.:.::|        ::.:..:..:..:|                      ||..||       
 Worm   261 LSDQQRIAVKRRQRTNRMLIGMVVAFACSW----------------------IWSVTFNILRDYE 303

  Fly   325 --------------------AKTSAVYNPIVYGISHPKYRIVLKEKCP 352
                                |.||.|:||::|.:.:.:.|....:..|
 Worm   304 YLPELIKTQEYIFGIATHCIAMTSTVWNPLLYAVLNLQLRAAFIDLMP 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh2NP_524398.1 7tm_4 67..>237 CDD:304433 41/174 (24%)
7tm_1 74..336 CDD:278431 59/301 (20%)
npr-4NP_001300304.1 TM helix 1 52..76 CDD:320331 8/26 (31%)
TM helix 2 85..107 CDD:320331 6/21 (29%)
TM helix 3 123..145 CDD:320331 4/21 (19%)
TM helix 4 166..182 CDD:320331 4/17 (24%)
TM helix 5 211..234 CDD:320331 5/22 (23%)
TM helix 6 273..298 CDD:320331 5/46 (11%)
TM helix 7 314..339 CDD:320331 7/24 (29%)
7tmA_NPYR-like 50..346 CDD:320331 66/331 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45695
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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