Protein Alignment Rh2 and RRH

DIOPT Version :10

• Sequence 1: NP_524398.1
• Gene: Rh2 / 42261
• FlyBaseID: FBgn0003248
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_006574.1
• Gene: RRH / 10692
• HGNCID: 10450
• Length: 337
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 91/309 - (29%)
• Similarity: 154/309 - (49%)
• Gaps: 40/309 - (12%)

  Fly    59 ILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETW 123
            |:..:.:...:||...|.:|:.||...|.||||.|.:::|||.:|..:.:...|:...:..|.:|
Human    27 IVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSW 91

  Fly   124 VLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWT 188
            ..|...|.:|||....||..||..:.::|.|||..|.....|..||..|.|..||..|:..:||.
Human    92 KFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWA 156

  Fly   189 VMPLIGWSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLFV----YYTPLFLICYSYWFIIAAVA 249
            :||:|||::|.|:.....|:|::..   |.||: ::|::.|    :..||.::.|.|:.:..::.
Human   157 LMPIIGWASYAPDPTGATCTINWRK---NDRSF-VSYTMTVIAINFIVPLTVMFYCYYHVTLSIK 217

  Fly   250 AHEKAMREQAKKMNVKSLRSSEDC------DKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF 308
            .|                 ::.||      |.|.:..:.|:::..|.::.:||:||.::|.:..|
Human   218 HH-----------------TTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASF 265

  Fly   309 ----KIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPKYR--IVLKEKC 351
                ||   .|...|....|||:|..|||.:|.:::.|:|  ::...||
Human   266 GDPKKI---PPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKC 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tmA_photoreceptors_insect	59..347	CDD:320207	89/303 (29%)
		TM helix 1	59..85	CDD:320207	7/25 (28%)
		TM helix 2	92..118	CDD:320207	6/25 (24%)
		TM helix 3	130..160	CDD:320207	12/29 (41%)
		TM helix 4	171..191	CDD:320207	7/19 (37%)
		TM helix 5	218..247	CDD:320207	8/32 (25%)
		TM helix 6	276..306	CDD:320207	8/29 (28%)
		TM helix 7	315..340	CDD:320207	10/24 (42%)
RRH	NP_006574.1	7tmA_Peropsin	26..305	CDD:320201	89/301 (30%)
		TM helix 1	27..53	CDD:320201	7/25 (28%)
		TM helix 2	60..87	CDD:320201	6/26 (23%)
		TM helix 3	98..128	CDD:320201	12/29 (41%)
		TM helix 4	141..159	CDD:320201	6/17 (35%)
		TM helix 5	186..216	CDD:320201	6/30 (20%)
		TM helix 6	233..263	CDD:320201	8/29 (28%)
		TM helix 7	273..298	CDD:320201	10/24 (42%)