Protein Alignment Rh2 and tmtops3b

DIOPT Version :10

• Sequence 1: NP_524398.1
• Gene: Rh2 / 42261
• FlyBaseID: FBgn0003248
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001269304.1
• Gene: tmtops3b / 102031126
• ZFINID: ZDB-GENE-091204-311
• Length: 379
• Species: Danio rerio
• Alignment Length: 390
• Identity: 101/390 - (25%)
• Similarity: 175/390 - (44%)
• Gaps: 55/390 - (14%)

  Fly    20 FQAQSSGNGSVLDNVLP-DMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFG 83
            |...||.|||:||::.| |........::       :::.|||:    |.:.....|.||:.:|.
Zfish     6 FLRDSSVNGSLLDSLSPADQTGFSRAGYT-------VVAVILGI----IFVFGFLCNFVVLLVFA 59

  Fly    84 GTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSM 148
            ....||||.||::||:..||..:....:|:......:..|:.|...|..|....:|||.||:.|:
Zfish    60 RFHVLRTPINLILLNIIVSDMLVCLFGTPLSFAASVHGRWLTGVHGCRWYGFANALFGIVSLVSL 124

  Fly   149 CMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMT 213
            .:::::||:.|:..........:.:.:.|...|:.::.|||.||:|||:|.|||..|.||:.:..
Zfish   125 AVLSYERYSTILCSSKADASDYRKAWLFITGCWLYSLLWTVPPLLGWSSYGPEGPGTTCSVQWNK 189

  Fly   214 RMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAE 278
            |....|||:|...:|....||.|:.|.|..|:.|:....|..:..|::               .|
Zfish   190 RSPETRSYVICLFVFCLLLPLLLMVYCYGKILIAIHGVAKINQTAAQR---------------RE 239

  Fly   279 GKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGLTPLTTIWGATFAKTSAVYNPIVYGI----- 338
            ..:..:.::.:|.:.:.|.||.|:...|.|.....:|..::..:..||:|.|.|||:|.:
Zfish   240 THVLVMVVSMVSCYLLCWMPYGVMALLGTFSAGITSPTASVVSSLLAKSSTVLNPIIYVLFNNQF 304

  Fly   339 -----------SHPKYRIVL-------KEKC-PMCVFGNTDEPKP----DAPASDTETTSEADSK 380
                       :.|...:.|       ::.| ||.::..|..|:.    |.|.....::.:..:|
Zfish   305 YRCFIALVRSGAEPPVHLTLHTEEGAAQQHCIPMGLYAATSPPESPSLMDTPQMTQNSSLQRGNK 369

  Fly   381  380
            Zfish   370  369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tmA_photoreceptors_insect	59..347	CDD:320207	82/303 (27%)
		TM helix 1	59..85	CDD:320207	8/25 (32%)
		TM helix 2	92..118	CDD:320207	7/25 (28%)
		TM helix 3	130..160	CDD:320207	10/29 (34%)
		TM helix 4	171..191	CDD:320207	5/19 (26%)
		TM helix 5	218..247	CDD:320207	11/28 (39%)
		TM helix 6	276..306	CDD:320207	6/29 (21%)
		TM helix 7	315..340	CDD:320207	9/40 (23%)
tmtops3b	NP_001269304.1	7tm_GPCRs	34..308	CDD:475119	81/299 (27%)
		TM helix 1	36..60	CDD:410628	8/27 (30%)
		TM helix 2	69..91	CDD:410628	7/21 (33%)
		TM helix 3	107..129	CDD:410628	7/21 (33%)
		TM helix 4	151..167	CDD:410628	5/15 (33%)
		TM helix 5	195..218	CDD:410628	9/22 (41%)
		TM helix 6	243..265	CDD:410628	5/21 (24%)
		TM helix 7	276..301	CDD:410628	9/24 (38%)