Protein Alignment Rh2 and gpr52

DIOPT Version :10

• Sequence 1: NP_524398.1
• Gene: Rh2 / 42261
• FlyBaseID: FBgn0003248
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: XP_068072548.1
• Gene: gpr52 / 101884270
• ZFINID: ZDB-GENE-050208-696
• Length: 370
• Species: Danio rerio
• Alignment Length: 370
• Identity: 80/370 - (21%)
• Similarity: 160/370 - (43%)
• Gaps: 50/370 - (13%)

  Fly    25 SGNGSVLDNVLPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSL- 88
            :.|||:..:....:.|.....|.:...::..:.:...:..|.::||:  ||..|:::|.....|
Zfish    12 TANGSLSGHFSVSLNHSCPLGWGQNKVLEACVLETAVIVLLTVLIIA--GNLTVIFVFHCAPLLH 74

  Fly    89 RTPANLLVLNLAFSDF-----CMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSM 148
            ....:..:..:|::|.     |::.:.|.:     :|...|..|:.|.:::...|:...||:..:
Zfish    75 HYTTSYFIQTMAYADLLVGLSCLVPTLSLL-----HYPAGVQEPITCQVFSYIISVLKSVSMACL 134

  Fly   149 CMIAFDRYNVIVKGIN----GTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSI 209
            ..|:.|||..|.|.::    .||..::..   |:.||:.:....:....||......|::    .
Zfish   135 ACISVDRYLAITKPLSYNQLVTPCRLRCC---IILIWIYSCVVFLPSFFGWGKPGYHGDI----F 192

  Fly   210 DYMTRMWNPRSYLIT-YSLFVYYTPLFL-ICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSED 272
            ::....| |.|.|.| :.:.:.|.|..| :|::|:.|......|.:.:.|:..:...:.:.::|.
Zfish   193 EWCANSW-PTSALFTGFVVCLLYAPAALVVCFTYFHIFRICQQHNREISERRARFPSQEMETTEG 256

  Fly   273 CDKSAEG---KLAKVALTTISLWFMAWTPYLVICYFGLFKIDGL-TP---LTTIWGATFAKTSAV 330
            .:.:..|   :.|.|.....|:::|.|.||  |.||.|.....| :|   ..|.|   .|.:::.
Zfish   257 GNPAGHGPDRRYAMVLFRITSVFYMLWLPY--IFYFLLESSHVLDSPALSFVTTW---LAISNSF 316

  Fly   331 YNPIVYGISHPKYRIVLKE----KCPMCVFG-------NTDEPKP 364
            .|.::|.:|:..:|:.::.    .|..|.|.       :..||||
Zfish   317 CNCVIYSLSNSVFRLGMRRLSQTLCSSCSFSPCTHDDKDFGEPKP 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tmA_photoreceptors_insect	59..347	CDD:320207	68/306 (22%)
		TM helix 1	59..85	CDD:320207	7/25 (28%)
		TM helix 2	92..118	CDD:320207	4/30 (13%)
		TM helix 3	130..160	CDD:320207	8/29 (28%)
		TM helix 4	171..191	CDD:320207	3/19 (16%)
		TM helix 5	218..247	CDD:320207	10/30 (33%)
		TM helix 6	276..306	CDD:320207	10/32 (31%)
		TM helix 7	315..340	CDD:320207	6/27 (22%)
gpr52	XP_068072548.1	7tm_classA_rhodopsin-like	45..326	CDD:410626	66/300 (22%)
		TM helix 1	45..70	CDD:410626	7/26 (27%)
		TM helix 2	78..104	CDD:410626	4/25 (16%)
		TM helix 3	116..146	CDD:410626	8/29 (28%)
		TM helix 4	159..178	CDD:410626	3/21 (14%)
		TM helix 5	202..227	CDD:410626	8/24 (33%)
		TM helix 6	253..293	CDD:410626	12/41 (29%)
		TM helix 7	301..326	CDD:410626	6/27 (22%)