Protein Alignment Rh2 and opn4

DIOPT Version :10

• Sequence 1: NP_524398.1
• Gene: Rh2 / 42261
• FlyBaseID: FBgn0003248
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: XP_002937616.1
• Gene: opn4 / 100491785
• XenbaseID: XB-GENE-484582
• Length: 592
• Species: Xenopus tropicalis
• Alignment Length: 415
• Identity: 131/415 - (31%)
• Similarity: 209/415 - (50%)
• Gaps: 78/415 - (18%)

  Fly     8 ETP-FDLAHSGPRFQAQSSGNGSVLDNVLPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIIS 71
            ||| :::.|..|...             :||..|.|                 :|...||:.|..
 Frog    49 ETPQYEIHHVYPTVD-------------VPDHVHYV-----------------VGAVILAVGITG 83

  Fly    72 CCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGC 136
            ..||.:|:|.|..::|||:|||:.::|||.:||.|..:|:||......::.|:.|...|::||.|
 Frog    84 MLGNFLVIYAFCRSRSLRSPANMFIINLAITDFLMSVTQAPVFFATSLHKRWIFGEKGCELYAFC 148

  Fly   137 GSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVP 200
            |:|||..|:.::.:||.|||.||.:.:... .|:.|.:::.:..:|:.::.|::.|..|||||||
 Frog   149 GALFGITSMITLMVIALDRYFVITRPLTSIGVMSKKRAVLILSGVWLYSLAWSLPPFFGWSAYVP 213

  Fly   201 EGNLTACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVK 265
            ||.||:|:.||||...:.|:|.:....||::.|||:|.|.|.||..|:....:|:::.....|.:
 Frog   214 EGLLTSCTWDYMTFTPSVRAYTMLLFCFVFFIPLFIIIYCYIFIFKAIKNTNRAVQKIGTDDNKE 278

  Fly   266 SLRSSEDCDKSAEGKLAKVALTTISLWFMAWTPY---LVICYFGLFKIDGLTPLTTIWGATFAKT 327
            |.:..:....  |.|:||:||..|.|:.::|:||   .::.:.|...:  |||......|..||.
 Frog   279 SHKQYQKMKN--EWKMAKIALIVILLYVVSWSPYSTVALVAFAGYASV--LTPYMNSVPAVIAKA 339

  Fly   328 SAVYNPIVYGISHPKYRIVLKEKCPMCV----------------------------------FGN 358
            ||::|||:|.|:|||||:.:.:..| |:                                  .|.
 Frog   340 SAIHNPIIYAITHPKYRMAIAKYIP-CLGSLLRVKRRDSRSYSSYPSSRRSTVTSHCSQSSDVGG 403

  Fly   359 TDEPKPDAPA-SDTE---TTSEADS 379
            ..:.|...|: ||:|   |.:||||
 Frog   404 HPKLKNHLPSVSDSESGWTDTEADS 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tmA_photoreceptors_insect	59..347	CDD:320207	109/291 (37%)
		TM helix 1	59..85	CDD:320207	9/25 (36%)
		TM helix 2	92..118	CDD:320207	11/25 (44%)
		TM helix 3	130..160	CDD:320207	15/29 (52%)
		TM helix 4	171..191	CDD:320207	3/19 (16%)
		TM helix 5	218..247	CDD:320207	12/28 (43%)
		TM helix 6	276..306	CDD:320207	11/32 (34%)
		TM helix 7	315..340	CDD:320207	11/24 (46%)
opn4	XP_002937616.1	7tmA_Melanopsin	70..359	CDD:320458	110/309 (36%)
		TM helix 1	71..97	CDD:320458	10/42 (24%)
		TM helix 2	104..130	CDD:320458	11/25 (44%)
		TM helix 3	142..172	CDD:320458	15/29 (52%)
		TM helix 4	184..206	CDD:320458	4/21 (19%)
		TM helix 5	231..261	CDD:320458	12/29 (41%)
		TM helix 6	287..317	CDD:320458	11/31 (35%)
		TM helix 7	327..352	CDD:320458	11/24 (46%)