DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh2 and opn1lw

DIOPT Version :9

Sequence 1:	NP_524398.1	Gene:	Rh2 / 42261	FlyBaseID:	FBgn0003248	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001096331.1	Gene:	opn1lw / 100124917	XenbaseID:	XB-GENE-955009	Length:	365	Species:	Xenopus tropicalis

Alignment Length:	345	Identity:	92/345 - (26%)
Similarity:	154/345 - (44%)	Gaps:	37/345 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCM 106
            :.|.|         :..|..|:.:.:::.|...||:|:......|.||.|.|.:::|:|.:|...
Frog    46 IAPRW---------VYNISSLWMIFVVLASVFTNGLVLVATLKFKKLRHPLNWILVNMAIADLGE 101

  Fly   107 MASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIK 171
            ....|.:.:.|..:..:|||...|.:.....|:.|..::||:.:||::|:.|:.|.........|
Frog   102 TVIASTISVCNQIFGYFVLGHPMCILEGYTVSVCGIAALWSLTVIAWERWFVVCKPFGNIKFDGK 166

  Fly   172 TSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNP--RSYLITYSLFVYYTPL 234
            .:...|:|.|:.|..|...|:.|||.|.|.|..|:|..|..:...:|  :||::...:.....||
Frog   167 LAATGIIFSWVWAAGWCAPPIFGWSRYWPHGLKTSCGPDVFSGSSDPGVQSYMLVLMITCCIIPL 231

  Fly   235 FLI--CYSY-WFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAW 296
            .:|  ||.: |..|..||..:|               .||...| ||.:::::.:..|..:...|
Frog   232 AIIVLCYMHVWLTIRQVAQQQK---------------ESESTQK-AEREVSRMVVVMIIAYIFCW 280

  Fly   297 TPYLVICYFGLFKID-GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVFG-NT 359
            .||.....|..|... ...||.....|.|||::.:||||:|...:.::|     .|...:|| ..
Frog   281 GPYTFFACFAAFNPGYNFHPLAAAMPAYFAKSATIYNPIIYVFMNRQFR-----NCIYQLFGKKV 340

  Fly   360 DEPKPDAPASDTETTSEADS 379
            |:....:..|.||.:|.::|
Frog   341 DDGSEVSSTSRTEVSSVSNS 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh2	NP_524398.1	7tm_4	67..>237	CDD:304433	48/171 (28%)
Rh2	NP_524398.1	7tm_1	74..336	CDD:278431	76/267 (28%)
opn1lw	NP_001096331.1	7tmA_LWS_opsin	41..332	CDD:320209	83/315 (26%)
		TM helix 1	54..80	CDD:320209	6/25 (24%)
		TM helix 2	87..114	CDD:320209	6/26 (23%)
		TM helix 3	125..155	CDD:320209	9/29 (31%)
		TM helix 4	166..188	CDD:320209	7/21 (33%)
		TM helix 5	215..245	CDD:320209	8/29 (28%)
		TM helix 6	260..290	CDD:320209	7/30 (23%)
		TM helix 7	300..325	CDD:320209	11/24 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910