Protein Alignment Octalpha2R and htr1b

DIOPT Version :9

• Sequence 1: NP_001262715.1
• Gene: Octalpha2R / 42258
• FlyBaseID: FBgn0038653
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001122181.1
• Gene: htr1b / 561647
• ZFINID: ZDB-GENE-081022-141
• Length: 380
• Species: Danio rerio
• Alignment Length: 640
• Identity: 153/640 - (23%)
• Similarity: 240/640 - (37%)
• Gaps: 269/640 - (42%)

  Fly    76 AGFYNQSSA-----SGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNML 135
            :|::..:.|     :.:|..|:|....|:...:       :....|..|.::.::.:..::.|..
Zfish     4 SGYFKPTPAHFEVLNSSTGTNVTLTPKTDEKQE-------SFAFQVTLSSVLGLITLATILSNAF 61

  Fly   136 VIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCT 200
            ||..|:..:.|:...|:.||||||.|..:.:::||..:...:...|..|...|||..:.|:..||
Zfish    62 VIATISQSRKLQTPANFLIASLAVTDLLVSVLVMPICVLYTVTREWTLGQVICDIWLSSDITCCT 126

  Fly   201 ASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPK 265
            |||::||:|:|||||:||.||:|.|.||.||||.|:...||::..|.:||....:||  .|.|..
Zfish   127 ASILHLCVIALDRYWAITDAVEYAKKRTQARAAGMVATAWIIAISISLPPFFWRQVK--AGELTT 189

  Fly   266 CELSED-IGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKK 329
            |.::.| |.|.:||..|:||||:.:::.:|.|||..|:   :|.:|:.|:|. .:::||...:..
Zfish   190 CSVNTDHIFYTIYSTFGAFYIPTLLLIALYGRIYVEAR---KRILKQSPKKP-GKRLTSAHLSTN 250

  Fly   330 GTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTV 394
            ....:.|:|     .||..||                      ||.||
Zfish   251 SPASVASTS-----PLHCGRQ----------------------DLCSD----------------- 271

  Fly   395 LAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSIN 459
                                      ||                            |:||:
Zfish   272 --------------------------SG----------------------------SLGSD---- 278

  Fly   460 VLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFD 524
                                                 |::||
Zfish   279 -------------------------------------NQIRV----------------------- 283

  Fly   525 PSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQ 589
             :.|||.:
Zfish   284 -TVSDSLL--------------------------------------------------------- 290

  Fly   590 QQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACS 654
                                   ||:||:..:|::||..||:|:|::|.||||||...:|:|.||
Zfish   291 -----------------------EKKRISAARERKATKTLGIILGAYIVCWLPFFIYTLLIPLCS 332

  Fly   655 SHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYR 709
            | |..|| .|....||||:||.:||.|||:.|.||::||.::     :::.||.|
Zfish   333 S-CFSPE-LFDFFTWLGYVNSLINPIIYTMSNDDFKKAFHKV-----ISFRCCRR 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octalpha2R	NP_001262715.1	7tm_1	132..>315	CDD:278431	75/183 (41%)
		7tm_4	133..>252	CDD:304433	52/118 (44%)
htr1b	NP_001122181.1	7tm_1	59..358	CDD:278431	134/549 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	1	1.000	-	-		X366
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940