DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octalpha2R and DopEcR

DIOPT Version :9

Sequence 1:	NP_001262715.1	Gene:	Octalpha2R / 42258	FlyBaseID:	FBgn0038653	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	64/221 - (28%)
Similarity:	107/221 - (48%)	Gaps:	13/221 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 SIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIF 183
            :::::||.:.||:.|:|:|...|..|....:.|:::.|||:||...||:::|||:...|.|.|::
  Fly    19 AVLISILGVAIVLSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVVPFSVYPALTGEWMY 83

  Fly   184 GSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICI 248
            |...|.....::|.|...|:.....||:|||.::.|.:.|...:|..|....:...||.:||:|.
  Fly    84 GDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMVFTWISAALLCC 148

  Fly   249 PPLLGWKVKMPEGPLPKCELSEDIG-YVLYSALGSFYI--PSCIMVFVYIRIYFAAKARARRGIK 310
            ||:||:.:.:.......|.|  |.| ...|||..:..:  ||.|.:.......|....:.|.|..
  Fly   149 PPILGYSMPIENNMTHICML--DWGNMAAYSATLAILVLGPSLISIVHNYGYIFVMMRKIRSGEP 211

  Fly   311 KHPRKTNNEQVTSFTTAKKGTIPMPS 336
            .|.::        :.||....:..||
  Fly   212 IHDKE--------YATALAENLSNPS 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octalpha2R	NP_001262715.1	7tm_1	132..>315	CDD:278431	56/185 (30%)
Octalpha2R	NP_001262715.1	7tm_4	133..>252	CDD:304433	40/118 (34%)
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	64/221 (29%)
		TM helix 1	18..42	CDD:410626	7/22 (32%)
		TM helix 2	51..73	CDD:410626	10/21 (48%)
		TM helix 3	89..111	CDD:410626	4/21 (19%)
		TM helix 4	134..150	CDD:410626	5/15 (33%)
		TM helix 5	174..197	CDD:410626	6/22 (27%)
		TM helix 6	230..252	CDD:410626	64/221 (29%)
		TM helix 7	264..289	CDD:410626
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010