Protein Alignment Octalpha2R and LOC100493940

DIOPT Version :9

• Sequence 1: NP_001262715.1
• Gene: Octalpha2R / 42258
• FlyBaseID: FBgn0038653
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_004912925.1
• Gene: LOC100493940 / 100493940
• -ID: -
• Length: 394
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 168/620 - (27%)
• Similarity: 243/620 - (39%)
• Gaps: 244/620 - (39%)

  Fly    78 FYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIAT 142
            |||.|..:.....|:         |.      ||.....:..|.|..:::..|:||:||::||.|
 Frog    11 FYNGSEETDQPQLNV---------WP------YTALECTLIIIAVVSIILSTVLGNILVVLAIFT 60

  Fly   143 EKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLC 207
            .::|:..||.|:.|||.||..:|.:|:|||||.|:||||.|||.||.::.|:|:|.||:||::||
 Frog    61 SRALRAPQNLFLVSLASADILVGALIIPFSLAREVMGYWHFGSVWCSMYLALDILFCTSSIVHLC 125

  Fly   208 LISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPKCELSEDI 272
            .||:|||||:||||.|...|||.|....|..:|::||:|..||||..|.|..|     |.|::|.
 Frog   126 AISIDRYWSVTKAVKYNLKRTPKRIKRSIAIIWVVSAIISFPPLLKSKHKEWE-----CLLNDDT 185

  Fly   273 GYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSS 337
            .|||:|...||::|..||:.:|.|||..||.|
 Frog   186 WYVLFSCTVSFFVPCLIMILLYCRIYRVAKHR--------------------------------- 217

  Fly   338 SGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNG 402
              ||:|:                            :..||.:::.||
 Frog   218 --VSSLR----------------------------NGVSDCNSAAAG------------------ 234

  Fly   403 AGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGT 467
                                                              |:..:.:.:.||:
 Frog   235 --------------------------------------------------GTCETHHTIQNNH-- 247

  Fly   468 VAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGV 532
                                                               ...|.|...|.|.|
 Frog   248 ---------------------------------------------------EAEELDLEESTSSV 261

  Fly   533 VSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSEL 597
            ..                |.:|..::.:...:.|.||.      .|.:..:.||.:.|.:..|::
 Frog   262 HK----------------FPKKHHHKTKDKPSSAKAKR------LSWSSNRGQQHRDQSICISQM 304

  Fly   598 EPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPES 662
                              |:.:.:|||.|.:|.:::|.|:.||.||||.|.|...|...|.|.::
 Frog   305 ------------------RLTQLREKRLTFVLAVVIGGFVICWFPFFFTYSLESVCRKRCGISDA 351

  Fly   663 AFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRIL 697
            .|...||:||.||:|||.|||:||:|||:||||||
 Frog   352 LFNFFFWIGYCNSSLNPIIYTVFNRDFRKAFRRIL 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octalpha2R	NP_001262715.1	7tm_1	132..>315	CDD:278431	89/182 (49%)
		7tm_4	133..>252	CDD:304433	64/118 (54%)
LOC100493940	XP_004912925.1	7tmA_alpha-2D_AR	34..382	CDD:320447	154/576 (27%)
		TM helix 1	35..61	CDD:320447	9/25 (36%)
		TM helix 2	68..94	CDD:320447	15/25 (60%)
		TM helix 3	106..136	CDD:320447	17/29 (59%)
		TM helix 4	148..171	CDD:320447	9/22 (41%)
		TM helix 5	184..213	CDD:320447	14/28 (50%)
		TM helix 6	309..339	CDD:320447	14/29 (48%)
		TM helix 7	350..375	CDD:320447	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	297	1.000	Domainoid score	I1441
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2375
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323202at33208
OrthoFinder	1	1.000	-	-		FOG0001303
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060