DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7720 and Smvt

DIOPT Version :9

Sequence 1:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster

Alignment Length:	574	Identity:	158/574 - (27%)
Similarity:	286/574 - (49%)	Gaps:	46/574 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVRSVLGYPSE 75
            ||.:|.|.::::....::...|.|.::.:: :|:.....:..:.:.||:....|...|::..|:|
  Fly    28 DYGVFALVLSISAAIGVYFGFFAKGEDTTE-EYLMGGKRMKTIPIAISLVASQLSAISIMTIPAE 91

  Fly    76 LYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRCLASATYIVRQIC 140
            :|..|......:..|:...|::.::.:||::|..||:.|:|:::|| .|.||.|.:..:|:....
  Fly    92 MYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVRVLQTFIFILTMFF 155

  Fly   141 NLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTILVVTVAVCIQ 205
            .|.|.::.||:|.:.|.|.......|.:..||:|:|:.||:||.:..||||...::...|.|.:.
  Fly   156 MLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVGVL 220

  Fly   206 GTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQIGCQQNFMQRYVSLK 270
            |....||..:|.::..:.|||:. |:..|:|.|....:.:.....|....:|..|:.:||.|||.
  Fly   221 GAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVSLP 284

  Fly   271 SLKQVRRVMLT---NVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPDEILPFFVEDQLGF 332
            ||...||.::.   ...|:.||   :..:|:||||.:.:|||...|::.|.|:::|:||:|.:|.
  Fly   285 SLGHARRSLVLFGFGFILIMFF---NCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGN 346

  Fly   333 LPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVVCGL-I 396
            |.|..|:|::.:|:.||..:.:::|||..|::.|:|.  |..:....:..: |:|......|: .
  Fly   347 LWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIK--PHIRHTEHRANV-IMKLFVFFTGIYC 408

  Fly   397 IMGVAFGVGLLAGVIESSLLVF----SATSGPLLGCFILAMMVPIANWKGTSAGMVT--ACAFVL 455
            |:|     |::.....|.|.|.    ..:.|...|.|:|.|:||.::.:....|::.  ||...:
  Fly   409 ILG-----GMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMATI 468

  Fly   456 WIIGGGMTVTKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQPTI 520
            .|:..|   ......|||||..|           |....|.:..:.:.:|:      |:.: .|.
  Fly   469 VILSWG---RNHYDTLPTSTSAC-----------PASLNGTIKDISTASPL------FLGS-TTE 512

  Fly   521 APERSGLETFYSISFMYYSLIGTALTVIIGTVIS-LLTQHPDDAYDGKLLHPLI 573
            ||......:...:||.:|::.|..:|.:||..:| :|...||...:.|||.|::
  Fly   513 APVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVV 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	151/555 (27%)
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	151/554 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970