DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7720 and salt

DIOPT Version :9

Sequence 1:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	631	Identity:	171/631 - (27%)
Similarity:	303/631 - (48%)	Gaps:	57/631 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDLSTMGWDYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVR 67
            :||.....||::|.|.::.:....::...|.|.|..:: :|:.....:..:.|.||:....|...
  Fly    21 EDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTE-EYLQGGKRMPTLPVAISLVSSQLSGV 84

  Fly    68 SVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRCLASA 132
            :::..|:|.|..|..|..:::.|:.:.|::.::.|||:::..:::.|:|::|||..|| |.|.:.
  Fly    85 AMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRT-RQLVTI 148

  Fly   133 TYIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTILV 197
            |:|:.|...|.:.::.||:|.|.|.|.......|.::.||:|:|::||:||.:..||:|...:|:
  Fly   149 TFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLI 213

  Fly   198 VTVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQIGCQQNF 262
            ..|.|.|.||.:|||:..|.:...:.||.:| :|..|..:|:...|.....|.|...::|..|:.
  Fly   214 SVVLVAILGTSNTGGITNVLENAAEGGRFDF-SFGIDPRLRLTFISGMASGLLMWTGKLGLDQSC 277

  Fly   263 MQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPDEILPFFVE 327
            :||.|||.|....:|.:|..........|.:..:|:::::.|..|||...|.:.|||:::|||::
  Fly   278 VQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQ 342

  Fly   328 DQLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVV 392
            |.:|.:.|..|:|::.:|:.:|..:.::|||.|.|::.|:|.  |:... |:.:....:|.:.||
  Fly   343 DIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIK--PRINH-SEAKANATMKLVIVV 404

  Fly   393 CGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAGMVTACAFVLWI 457
            .|...:...|.|.....:|::...:.....|.::|.|.|.|.||..|.|...:|:..:|..:|||
  Fly   405 MGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWI 469

  Fly   458 IGGGMT-----VTKDNPLLPTSTDGCTNDTF-----------AQSIGKPIVEQGQMPWLLSHTPI 506
            |..|..     :.|.:| ||...|.|....|           ..::|...:...:.|..|: |..
  Fly   470 IINGQMNFKAGLIKYDP-LPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELT-TAF 532

  Fly   507 DGFNQSFVPTQPTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQHP---DDAYDGKL 568
            |. |:.|               :.|..||.:|.::|..|  :....|.:....|   ::..:.||
  Fly   533 DS-NRDF---------------SIYDTSFYWYKVLGALL--VFAWAIPMSYVWPLDKEEKQNPKL 579

  Fly   569 LHPLIFRLCERFSGRKPYYVKHEEESGLNG-------RSSSDSSAT 607
            ..|.:     |....||..|...||..|..       :...:.|||
  Fly   580 YSPFV-----RSMLNKPSPVLELEELPLKTPLSEEQIKEKENGSAT 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	155/561 (28%)
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	155/563 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970