DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7720 and CG42235

DIOPT Version :9

Sequence 1:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_651446.2	Gene:	CG42235 / 43136	FlyBaseID:	FBgn0250757	Length:	698	Species:	Drosophila melanogaster

Alignment Length:	643	Identity:	175/643 - (27%)
Similarity:	300/643 - (46%)	Gaps:	89/643 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DYLMFVLFIAL-TVLGPLWKRIFGKKKERSKA-------------------DYVFATGGVSIVAV 55
            |||:|:..:|: .|:|..:..|..|:|::..|                   ||:.....:.:..|
  Fly   106 DYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPV 170

  Fly    56 MISIARGTLGVRSVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLR 120
            .:|:....:...|:||..:|:|..|:....|:..:..:..|..::|:||:.||.:||.|:|.:.|
  Fly   171 ALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERR 235

  Fly   121 FKSRTVRCLASATYIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAI 185
            | .|.||...|..::|..|....|.:|.|::.|:.|.||.....:...:.|||.:|.:||:|..:
  Fly   236 F-DRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVV 299

  Fly   186 NADVIQTVTILVVTVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLF 250
            ..||||...::...:.|.|:||:..||:..|...||...||...:.|.|.|.|:...:.::|...
  Fly   300 WTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGVFALFVGGAL 364

  Fly   251 MSLSQIGCQQNFMQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYI 315
            ..|...|..|..:|||::|.:.|.|::.::.::....|...:....|::.::.:.:|||...|..
  Fly   365 FKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLLAFAEFYHCDPITTGLA 429

  Fly   316 KKPDEILPFFVEDQLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDK 380
            :..|:::|.:|...:|.:||.||:|:|.:|:.||..:.:.||||:.||..||:....| |.|:::
  Fly   430 RAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRK-KPLTER 493

  Fly   381 QQLRILKSITVVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSA 445
            |...:|:.:.:..|||.|.....|..|..|::.|..|.:.|.|||||.|.:.|::|....:....
  Fly   494 QTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLT 558

  Fly   446 GMVTACAFVLWII--------GGGMTVTKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMP--WL 500
            |:..|.:|..:|:        .|.:|.    |..|.|...| :.||            .:|  |
  Fly   559 GISCASSFTAYIVVRAQIAIFTGSLTF----PAKPVSIQDC-DYTF------------DLPANW- 605

  Fly   501 LSHTPIDGFNQSFVPTQPTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLL---TQHPDD 562
                          ....|..|..|.....:.|||::|:.:|:..|| :|::::.|   .|.| .
  Fly   606 --------------NATTTATPTESTSHGIHEISFLWYTAVGSVGTV-LGSLLATLYFGRQDP-R 654

  Fly   563 AYDGKLLHPLIFRLCERFSGRKPYYVKH-----EEESGLNGRSSSDSSATTTTCKAEK 615
            ..|.:|:.|::         ||.:|.|:     ||::..|...|.      |..|.|:
  Fly   655 VVDKELISPVL---------RKFWYGKYESVASEEKNNFNLHESE------TQLKLEQ 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	158/574 (28%)
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	158/574 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I385
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970