DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7720 and ChT

DIOPT Version :9

Sequence 1:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_650743.1	Gene:	ChT / 42245	FlyBaseID:	FBgn0038641	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	98/500 - (19%)
Similarity:	186/500 - (37%)	Gaps:	105/500 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VLFIALTVLGPLWKRIFGKKKER---SKADYVFATGGVSIVAVMISIARGTLGVRSVLGYPSELY 77
            |||..|.::..:|.   |:||:.   |:.:.:.|...:.:...:.::....:|...:.|....:|
  Fly    11 VLFYLLILVVGIWA---GRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIY 72

  Fly    78 YRGSAMWEIIYGMMSAYPIVCFMFVPVYF-----NLGITSVYQYIDLRFKSRTVRCLASATYIVR 137
            ..|....:..:|.     .:..:|..::|     ..|..::...:...|..|     ......:.
  Fly    73 TSGLVWCQAPFGY-----ALSLVFGGIFFANPMRKQGYITMLDPLQDSFGER-----MGGLLFLP 127

  Fly   138 QICN-----------LGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQ 191
            .:|.           ||.|       ||.:|.:.:..|:...:.|.||:|:.|||.:....||||
  Fly   128 ALCGEVFWAAGILAALGAT-------LSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQ 185

  Fly   192 TVTILVVTVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQI 256
            ...|. :.:.:||....|...|..:..|..|      |      ...|:....||...:..|...
  Fly   186 LFCIF-IGLWMCIPFAWSNEHVGSLSDLEVD------W------IGHVEPKKHWLYIDYGLLLVF 237

  Fly   257 G--CQQNFMQRYVSLKSLKQVRRV--------MLTNVPLVFFFFSISWISGMVIYSTYINCDPYA 311
            |  ..|.:.||.:|.|:..:.:.:        :|..:|.|        :.|.:..:|..|...|.
  Fly   238 GGIPWQVYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPV--------LIGAIAKATPWNETDYK 294

  Fly   312 EGYIKKPDE---ILPFFVEDQLGFL-PGFVGIF-----MATLFNGALCMMVSNLNSLATVIWEDF 367
            ..|....||   |||..::    :| |.||..|     .|.:.:.|...::|..:..|..:::..
  Fly   295 GPYPLTVDETSMILPMVLQ----YLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLI 355

  Fly   368 ISQLPKFKGLSDKQQLRILKSITVVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILA 432
            ..|     ..|:.:.:.:::...:|.|::       ..::|..|.|...::|..| .|:...:..
  Fly   356 FRQ-----KASEMEIIWVMRVAIIVVGIL-------ATIMALTIPSIYGLWSMCS-DLVYVILFP 407

  Fly   433 MMVPIANWK------GTSAGMVTACAFVLWIIGGGMTVTKDNPLL 471
            .::.:.::|      |:.:..:.|.|..|   .||..:....||:
  Fly   408 QLLMVVHFKKHCNTYGSLSAYIVALAIRL---SGGEAILGLAPLI 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	98/499 (20%)
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	98/499 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810