Protein Alignment CG7720 and Slc5a9

DIOPT Version :10

• Sequence 1: NP_650753.1
• Gene: CG7720 / 42257
• FlyBaseID: FBgn0038652
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001382057.1
• Gene: Slc5a9 / 366441
• RGDID: 1311383
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 145/750 - (19%)
• Similarity: 280/750 - (37%)
• Gaps: 211/750 - (28%)

  Fly     1 MAKDLSTMGWDYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATG--------GVSIVA--- 54
            :...:|...:|.::.|::....:...:|..|   :..|......|..|        |.|:::
  Rat    26 LGSGVSLHTYDIVVVVIYFVFVLAVGIWSSI---RASRGTIGGYFLAGRSMTWWPIGASLMSSNV 87

  Fly    55 ---VMISIA-RGTLGVRSVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQ 115
               :.|.:| .|..|..:|.|:.          |...:.:::    :.::|||||...|:.::.|
  Rat    88 GSGLFIGLAGTGAAGGLAVGGFE----------WNATFLLLA----LGWIFVPVYIAAGVVTMPQ 138

  Fly   116 YIDLRFKSRTVRCLASATYIVRQI-CNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMG 179
            |:..||..:.::...|...::..| ..:...:::.::.:...:|...:.|...:.|:...:||.|
  Rat   139 YLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTVILLVVTAVYTIAG 203

  Fly   180 GLKAAINADVIQTVTILVVTVAVCIQGTISTG---GVKKVYQLNRDN----------GRLNFWNF 231
            ||.|.|..|.:|||.::...:.:...|....|   |::::|:.:..|          .|.:.::.
  Rat   204 GLTAVIYTDALQTVIMVGGALVLMFLGFREVGWYPGLQQLYRQSIPNVTVPNTTCHLPRSDAFHM 268

  Fly   232 TGDMTVRVDTTSAWLGQLF-MSLSQIGC---QQNFMQRYVSLKSLKQVR--RVMLTNVPLVFFFF 290
            ..|   .|:....|.|.:| :::....|   .|..:||.:|.|||...:  .|:...:.::..||
  Rat   269 LRD---PVNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFF 330

  Fly   291 SISWISGMVIYSTYINCDPYAEGYIKKPDEI----------------------LPFFVEDQLGFL 333
            .:  :.||:..:.|             |||:                      .|..|   :..:
  Rat   331 IV--MPGMISRALY-------------PDEVACVDPDICQRVCGARVGCSNIAYPKLV---MALM 377

  Fly   334 P-GFVGIFMATLFNGALCMMVSNLNSLATV----IWEDFISQLPKFKGLSDKQQLRILKSITVVC 393
            | |..|:.:|.:....:..:.|..||.:|:    :|:       :.:..:.:|:|.::..:.||.
  Rat   378 PVGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVWQ-------RVRRQASEQELMVVGRLFVVF 435

  Fly   394 GLIIMGVAF-------GVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAGMVTAC 451
             |:::.:.:       ..|.|...|:|   :.|..:.|:...|:||:...    :.|..|
  Rat   436 -LVLISILWIPIIQSSNSGQLFDYIQS---ITSYLAPPITALFLLAIFCK----RVTEPG----- 487

  Fly   452 AFVLWIIGGGMTVTKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPT 516
            ||  |.:..|:.|.....:|..|..       |.:.|    |:.:.|.:|.
  Rat   488 AF--WGLMFGLVVGILRMILEFSYS-------APACG----EKDRRPAVLK-------------- 525

  Fly   517 QPTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQH-PDDAYDGKLLHPLIF-RLCER 579
                           ...::|::|:...||.||..:||..|:. ||:    ||.....: |.|..
  Rat   526 ---------------DFHYLYFALLLCGLTAIIIVIISFFTEPIPDE----KLARLTWWTRSCPI 571

  Fly   580 FSGRKPYYV-----KHEEESGLNGR-----SSSDSSATTTTCKAEKVNHGYESSPEDKEKSSPIA 634
            ...:|...|     :.:....|.||     ::.|.....||           |.||..|
  Rat   572 SELQKKVSVSVNNTESDNSPALAGRPVMEGTAGDEEEANTT-----------SEPEQPE------ 619

  Fly   635 VVFTTSEG-------TGSAG-DQQSICDSSRIQLD 661
             |...|.|       .|.:| .||::..:.:.:|:
  Rat   620 -VLHRSWGKWLWNWFCGLSGTPQQALSPAEKAELE 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_650753.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	117/614 (19%)
Slc5a9	NP_001382057.1	SLC5-6-like_sbd	48..688	CDD:444915	142/727 (20%)