Protein Alignment CG7720 and Slc5a12

DIOPT Version :9

• Sequence 1: NP_001163649.1
• Gene: CG7720 / 42257
• FlyBaseID: FBgn0038652
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001003915.1
• Gene: Slc5a12 / 241612
• MGIID: 2138890
• Length: 623
• Species: Mus musculus
• Alignment Length: 674
• Identity: 187/674 - (27%)
• Similarity: 316/674 - (46%)
• Gaps: 116/674 - (17%)

  Fly    10 WDYLMFV-LFIALTVLGPLWKRIFGKKKERSK-ADYVFATGG--VSIVAVMISIARGTLGVRSVL 70
            |||::|. ||:..:.:|     :|...|||.| ....|..||  :|...|.:|:....:...:||
Mouse     9 WDYVVFAGLFVISSGIG-----VFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVL 68

  Fly    71 GYPSELYYRGSAMWEIIYGMMSAYPIVCF----MFVPVYFNLGITSVYQYIDLRFKSRTVRCLAS 131
            |.|:|:|..|::    .:..:.:|..|.|    :|:||::..||||.|:|:.||| ::.||..|:
Mouse    69 GTPAEVYRFGAS----FFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRF-NKPVRYAAT 128

  Fly   132 ATYIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTIL 196
            ..|||:.|...|:.||.|::||:.|.|...|||:....::|.|:..:|||||.:..|..|.|.::
Mouse   129 IIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMI 193

  Fly   197 VVTVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGD-------MTVRVDTTSAWLGQLFMSLS 254
            |..:.|.|||:...||...|.:...:..||:..:|..|       .|:.:..|..|||
Mouse   194 VGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLG------- 251

  Fly   255 QIGCQQNFMQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPD 319
            ..|..|:.:||.:|.|:.|..:..:..|:..::...:.:..||:::||.:.:|||:..|.|..||
Mouse   252 VYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPD 316

  Fly   320 EILPFFVEDQLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLR 384
            :::|:||.:....:||..|:|:|..|:|.|..:.:::|:||||.:|||:...  |..||||....
Mouse   317 QLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSC--FPHLSDKLSTW 379

  Fly   385 ILKSITVVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCF---ILAMMVPIANWK---GT 443
            |.|.:.::.|::...:|....|:..|:::..:|  :....:.|.|   :.::...::.||   |.
Mouse   380 ISKGLCILFGIMCTSMAVVASLMGSVVQAPGIV--SQERAITGSFQRNLASVCYGVSIWKLIMGA 442

  Fly   444 SAGMVTACAFVLWIIGGGMTV----TKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHT 504
            ..|::|......|:..|....    :|..| ||.||:.|.......::...|
Mouse   443 LGGLLTGITLSFWVAIGSFIYPAPESKTLP-LPLSTEHCVELNITTTVAPQI------------- 493

  Fly   505 PIDGFNQSFVPTQPTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQHPDDAYDGKLL 569
                      .::|.:|      :|:||:|::|:|.:|....:..|.:||.||    ....||.:
Mouse   494 ----------SSRPVLA------DTWYSLSYLYFSAVGCLGCIAAGIIISFLT----GKQRGKDI 538

  Fly   570 HPLIFR-LCERFSGRKPYY-------VKHEE-----------------ESGLNGRSSSDSSATTT 609
            .||:.| :|..|......|       |:|:.                 ||||......|:.|...
Mouse   539 DPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIP 603

  Fly   610 TCKAEKVNHGYESSPEDKEKSSPI 633
                     ||  :|::|..|:.:
Mouse   604 ---------GY--NPKEKSYSNSV 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	164/570 (29%)
Slc5a12	NP_001003915.1	SLC5-6-like_sbd	3..531	CDD:294310	166/576 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810