Protein Alignment CG7720 and Slc5a11

DIOPT Version :10

• Sequence 1: NP_650753.1
• Gene: CG7720 / 42257
• FlyBaseID: FBgn0038652
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_666310.1
• Gene: Slc5a11 / 233836
• MGIID: 1919316
• Length: 673
• Species: Mus musculus
• Alignment Length: 717
• Identity: 146/717 - (20%)
• Similarity: 260/717 - (36%)
• Gaps: 202/717 - (28%)

  Fly    12 YLMFVLFIALTVLGPLWKRIFGKKKERSKAD----YVFATG-------GVSIVAVMISIAR--GT 63
            |.:|||.:.      ||..:      |:|.|    |..|.|       |.|:.|..:....  |.
Mouse    35 YFLFVLAVG------LWSTV------RTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGL 87

  Fly    64 LGVRSVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRC 128
            .|..:.:|.....|.        :.|:.|.. ::.::|:|:|....:|::.:|:..||....:..
Mouse    88 AGSGAAVGISVAAYE--------LNGLFSVL-MLAWVFLPIYIAGQVTTMPEYLRRRFGGNRISI 143

  Fly   129 LASATYIVRQI-CNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQT 192
            ..:..|:...| ..:.:.:|..::.:...:.:..:.:|.|:..|...:|:.|||.|.|..|.:||
Mouse   144 TLAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITALYTVAGGLAAVIYTDALQT 208

  Fly   193 VTILVVTVAVCIQGTISTG---GVKKVYQL----NR-DNGRLN------FWNFTGDMTVRVDTTS 243
            |.:|:....:......:.|   |:|..|.|    || :|....      |..|...:|    :..
Mouse   209 VIMLIGAFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDPLT----SDL 269

  Fly   244 AWLGQLF-MSLSQI--GC-QQNFMQRYVSLKSLKQVR-----RVMLTNVPLVFFFFSISWISGMV 299
            .|.|.|| ||:..:  .| .|..:||.::.|:|...:     ...|..:||....|     .|||
Mouse   270 PWPGILFGMSIPSLWYWCTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVF-----PGMV 329

  Fly   300 -------------------IYSTYINCDPYAEGYIKKPDEILPFFVEDQLGFLPGFVGIFMATLF 345
                               :.|....|...|  |.|...|:||          .|..|:.||.:.
Mouse   330 SRVLFPDQVACAHPDICQRVCSNPSGCSDIA--YPKLVLELLP----------TGLRGLMMAVMV 382

  Fly   346 NGALCMMVSNLNSLATVIWEDFISQL-PKFKGLSDKQQLRILKSITVVCGLIIMGVAFGVGLLAG 409
            ...:..:.|..||.:|:...|..:.: |:    :.:::|.|:..| .|..|:::.:     |...
Mouse   383 AALMSSLTSIFNSASTIFTMDLWNHIRPR----ASERELMIVGRI-FVFALVLVSI-----LWIP 437

  Fly   410 VIESS----LLVF-----SATSGPLLGCFILAMMVPIANWKGTSAGMVTACAFVLWIIGGGMTVT 465
            ::::|    |.::     |....|:...||:.......|.||..:|:      :|.::.|.:.:.
Mouse   438 IVQASQGGQLFIYIQSISSYLQPPVAMVFIMGCFWKRTNEKGAFSGL------ILGLLLGLVRLI 496

  Fly   466 KDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQPTIAPERSGLETF 530
            .|             ..:||    |..:|          |.|         :|.:..:
Mouse   497 LD-------------FVYAQ----PRCDQ----------PDD---------RPAVVKD------- 518

  Fly   531 YSISFMYYSLIGTALTVIIGTVISLLTQHPDDAYDGKLL----H-------------PLIFRLCE 578
              :.::|:|:|.:..|:|....:|..|:.|......:|.    |             ||...|.:
Mouse   519 --VHYLYFSMILSFTTLITVVTVSWFTETPSKEMVSRLTWFTRHEPVAQKDSAPPETPLSLTLSQ 581

  Fly   579 RFSGRKP---YYVKHEEES-------GLNGRSSSDSSATTTTCKAEKVNHGYESSPEDKEKSSPI 633
            ..:...|   ..::..:||       |::.|.|....|....|..||      :..|...|:.|:
Mouse   582 NGTTEAPGTSIQLETVQESTTKACGDGVSPRHSKVVRAILWLCGMEK------NKEEPPSKAEPV 640

  Fly   634 AV 635
            .|
Mouse   641 IV 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_650753.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	125/609 (21%)
Slc5a11	NP_666310.1	SLC5-6-like_sbd	28..673	CDD:444915	146/717 (20%)