Protein Alignment CG7720 and SLC5A8

DIOPT Version :9

• Sequence 1: NP_001163649.1
• Gene: CG7720 / 42257
• FlyBaseID: FBgn0038652
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_666018.3
• Gene: SLC5A8 / 160728
• HGNCID: 19119
• Length: 610
• Species: Homo sapiens
• Alignment Length: 623
• Identity: 188/623 - (30%)
• Similarity: 315/623 - (50%)
• Gaps: 52/623 - (8%)

  Fly    10 WDYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVRSVLGYPS 74
            |||::|...:.::....::....|..::.|| |::.....::.|.|.:|:....:...:|||.||
Human    13 WDYVVFAGMLVISAAIGIYYAFAGGGQQTSK-DFLMGGRRMTAVPVALSLTASFMSAVTVLGTPS 76

  Fly    75 ELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRCLASATYIVRQI 139
            |:|..|:......:.......|...:|:||::.|||||.|:|::||| ::.||...:..:||:.|
Human    77 EVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF-NKCVRLCGTVLFIVQTI 140

  Fly   140 CNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTILVVTVAVCI 204
            ...||.:|.|::||:.|.|...|.::....|:|.|:..:|||||.|..||.|...::....:|.|
Human   141 LYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVII 205

  Fly   205 QGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQIGCQQNFMQRYVSL 269
            |..:..||:..:.....|.||||||||..:...|....:..:|..|...|..|..|:.:|||:|.
Human   206 QAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISC 270

  Fly   270 KSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPDEILPFFVEDQLGFLP 334
            ||..|.:..:..|:..::...:.|...|:.:||.|.:|||:....:..||:::|:.|.|.|...|
Human   271 KSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYP 335

  Fly   335 GFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVVCGLIIMG 399
            |..|:|:|..::|.|..:.|::|:||.|..||.|.  |.|:.||::....|.:.::||.|.:.:|
Human   336 GLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIK--PYFRSLSERSLSWISQGMSVVYGALCIG 398

  Fly   400 VAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAGMVTACAFVLWI-IGGGMT 463
            :|....|:..:::::|.||....|||:|.|.|.::||.||..|...|::...|..||: ||..:.
Human   399 MAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIY 463

  Fly   464 VTKDNPLLPTSTD--GCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQPTIAPERSG 526
            .......||...|  || |.|:.::   .::...:||:..|...|  :|....|.
Human   464 PPLPERTLPLHLDIQGC-NSTYNET---NLMTTTEMPFTTSVFQI--YNVQRTPL---------- 512

  Fly   527 LETFYSISFMYYSLIGTALTVIIGTVISLLT----QHPDDAY----DGKLLHPLIFRLCERFSGR 583
            ::.:||:|::|:|.:||.:|:::|.::||.|    |:.|..|    :..|.:..||:       :
Human   513 MDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGRKQNLDPRYILTKEDFLSNFDIFK-------K 570

  Fly   584 KPY---YVKHEEESG-----------LNGRSSSDSSAT 607
            |.:   |..|..|.|           ||...|..|:.|
Human   571 KKHVLSYKSHPVEDGGTDNPAFNHIELNSDQSGKSNGT 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	170/548 (31%)
SLC5A8	NP_666018.3	SLC5sbd_SMCT1	7..549	CDD:271402	172/555 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820