DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7720 and Slc5a10

DIOPT Version :9

Sequence 1:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_006532041.1	Gene:	Slc5a10 / 109342	MGIID:	1926089	Length:	611	Species:	Mus musculus

Alignment Length:	504	Identity:	99/504 - (19%)
Similarity:	184/504 - (36%)	Gaps:	128/504 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATG--------GVSIVA------VMISIA- 60
            |.::..::.||.|...:|...   :..::.....|..|        |.|:.|      :.:.:|
Mouse    55 DIIVISVYFALNVAVGIWSAC---RANKNTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGLAG 116

  Fly    61 RGTLGVRSVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRT 125
            .|..|..:|.|:.          |.|:                        ::.:||..||..:.
Mouse   117 SGAAGGLAVAGFE----------WNIV------------------------TLPEYIQKRFGGQR 147

  Fly   126 VRCLASATYIVRQI-CNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADV 189
            :|...|...::..: ..:.|.:|..::.:...:|..::.|......|...:||.|||...|..|.
Mouse   148 IRTYLSVLSLMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDA 212

  Fly   190 IQTVTILVVTVAVCIQGTISTGGVKKV-----------------YQLNRDNGRLNFWN-FTGDMT 236
            :||:.::|..|.:.::.....||.:::                 ..|.|.:....|.: .|||:
Mouse   213 LQTIIMVVGAVILAVKAFNQIGGYEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDL- 276

  Fly   237 VRVDTTSAWLGQLF---MSLSQIGC-QQNFMQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISG 297
                   .|.|..|   :..:...| .|..:||.:|.::|...:...:....|......:..:.|
Mouse   277 -------PWTGMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPG 334

  Fly   298 M---VIYSTYINCDPYAE--------------GYIKKPDEILPFFVEDQLGFLPGFVGIFMATLF 345
            |   |::...:.|...:|              .|.|...|::|.          |..|:.:|.:.
Mouse   335 MISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPI----------GLRGLMIAVMM 389

  Fly   346 NGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVVCGLIIMGVAFG-VGLLAG 409
            ...|..:.|..||.:|:...|...||....|   :::|.::..:.:|   :::||:.. :.:|.|
Mouse   390 AALLSSLTSIFNSSSTLFTMDIWRQLRPSAG---ERELLLVGRLVIV---VLIGVSVAWIPVLQG 448

  Fly   410 VIESSLLVF--SATSG---PLLGCFILAMMVPIAN-----WKGTSAGMV 448
            .....|.::  |.||.   |:...|||.:....||     | |..||:|
Mouse   449 SNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFW-GLMAGLV 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	99/504 (20%)
Slc5a10	XP_006532041.1	SLC5-6-like_sbd	52..611	CDD:382020	99/504 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810