Protein Alignment CG7720 and slc5a11

DIOPT Version :10

• Sequence 1: NP_650753.1
• Gene: CG7720 / 42257
• FlyBaseID: FBgn0038652
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_004918107.1
• Gene: slc5a11 / 100488766
• XenbaseID: XB-GENE-1010719
• Length: 674
• Species: Xenopus tropicalis
• Alignment Length: 719
• Identity: 139/719 - (19%)
• Similarity: 261/719 - (36%)
• Gaps: 194/719 - (26%)

  Fly     3 KDLSTMGWDYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVR 67
            |.|.|:  |.::.||:....:...||.  ..:.|..:...|..|...::...|..|:....:|..
 Frog    21 KSLETV--DIVVLVLYFVFVLGVGLWS--ICRTKRGTVKGYFLAGKDMAWWPVGASLFASNVGSG 81

  Fly    68 SVLGYPSELYYRGSAM----WEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRC 128
            ..:|........|.|:    |..::.:::    :.::|:|:|.:.|:|::.:|:..||..:.::.
 Frog    82 HFIGLAGSGAASGIAVTAYEWNGLFCVLA----LAWLFLPIYISAGVTTMPEYLQRRFGGKRIQI 142

  Fly   129 LASATYIVRQI-CNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQT 192
            ..:..|:...| ..:.:.:|..::.:...:....:.::.|:.||...:|:.|||.|.|..|.:||
 Frog   143 FLAILYLFIYIFTKISVDMYAGALFIQQALQWDLYVAVIGLLVITAIYTVAGGLAAVIYTDTLQT 207

  Fly   193 VTILVVTVAVCIQGTISTGGV----KKVYQL--NRDNGRLN--------FWNFTGDMTVRVDTTS 243
            |.:::..:.:.....|..||.    :|.:|.  |..:|...        |..|...:|..:....
 Frog   208 VIMIIGALILMAYSFIEIGGFEALQEKYFQAIPNTHSGNSTCGIPREDAFHIFRDPVTSDLPWPG 272

  Fly   244 AWLGQLFMSLSQIGCQQNFMQRYVSLKSLKQVR-----RVMLTNVPLVFFFFSISWISGMVIYST 303
            ..:|....||......|..:||.:|.|:|...:     ...|..:||  |...:..:...|:::.
 Frog   273 VLVGMTIPSLWYWCTDQVIVQRSLSAKNLSHAKGGSLLAASLKVLPL--FMMVLPGMISRVLFTD 335

  Fly   304 YINC-DPYA-------------EGYIKKPDEILPFFVEDQLGFLPGFVGIFMATLFNGALCMMVS 354
            .:.| ||..             ..|.|...|:||          .|..|:.|:.:....:..:.|
 Frog   336 QVACADPELCKEICGNPSGCSDIAYPKMVIELLP----------TGLRGLMMSVMIAALMSSLTS 390

  Fly   355 NLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVVCGLIIMGVAFGVGLLAGVIESSL---L 416
            ..||.:|:...|.               .|.::..:....|:|:|..|   :||.|:.|.|   |
 Frog   391 IFNSASTIFTMDL---------------WRHIRPRSTEWELMIVGRVF---VLALVVVSILWIPL 437

  Fly   417 VFSATSGPLL--------------------GCFILAMMVPIANWKGTSAGMVTACAFVLWIIGGG 461
            |.::..|.|.                    |||          ||.|:    ...||  |    |
 Frog   438 VQASQGGQLFIYIQSISSYLQPPVAVVFIAGCF----------WKRTN----EKGAF--W----G 482

  Fly   462 MTVTKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQPTIAPE--- 523
            ||:                   ..::|            |....:|     |:    .:||:
 Frog   483 MTI-------------------GLAVG------------LIRMVLD-----FI----YVAPQCDQ 507

  Fly   524 ---RSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQHPD----------DAYDGKLLHPLI-- 573
               |.|:..:  :.::|.|:|...||:|:...:|:.|:.|.          ..:|.:::.|:.
 Frog   508 PDTRPGVVKY--VHYLYLSMILGLLTLIVVVAVSIWTEPPSKQMISRLTWFSRFDTEVVGPVETT 570

  Fly   574 --------FRLCERFSGRKPYYVKHEEESGLNGRSSSDSSATTTTCKAEKVNH--GYESSPEDKE 628
                    ..:.|..| .||    |...:........|.:.::::|..:.:..  |.:|...||.
 Frog   571 DNSPAQNGISVMEDIS-EKP----HATSTDAIYNDIIDDNPSSSSCLKKTILWLCGMDSRKGDKH 630

  Fly   629 KSSP 632
            ..:|
 Frog   631 DQAP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7720	NP_650753.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	120/612 (20%)
slc5a11	XP_004918107.1	SLC5sbd_SGLT6	27..674	CDD:271381	136/711 (19%)