Protein Alignment PGS1 and clsA

DIOPT Version :10

• Sequence 1: NP_650751.3
• Gene: PGS1 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_415765.1
• Gene: clsA / 945821
• ECOCYCID: EG11608
• Length: 486
• Species: Escherichia coli
• Alignment Length: 511
• Identity: 94/511 - (18%)
• Similarity: 170/511 - (33%)
• Gaps: 173/511 - (33%)

  Fly    47 WLHNL---------------APCFPL----------RGDQIQVIHEPKHFYETLVQRIGQAKRRI 86
            ||::|               ||.|.|          :|:|:|::.|.....:.|::.|..|:..|
E. coli    81 WLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNI 145

  Fly    87 VLASLYLGTGQLENAMVQTLRHSLEQQSALRLNVLLD------FTRG-------TRGTLNSKTML 138
            .:.......|.:.:.:.::|..:..:  .:...::||      |.|.       ..|....:.:.
E. coli   146 EMVFYIWQPGGMADQVAESLMAAARR--GIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALK 208

  Fly   139 LPLVRDFASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYLFDDAVIISGANLSND--YF 201
            :.|:|.|..::        |||                 ||.|:.:.|:.:..:|:....|  ||
E. coli   209 VNLMRVFLRRM--------DLR-----------------QHRKMIMIDNYIAYTGSMNMVDPRYF 248

  Fly   202 TNRQDRYILIEDKPLADFYAQFIERVQEFSLAVAPDASEGLHRNW------RILPYEGTKEQFIQ 260
              :||..:           .|:|:.:......:|.........:|      ||||
E. coli   249 --KQDAGV-----------GQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILP---------- 290

  Fly   261 LARKRISDLVQETFQRQARTKEQNPQADTWIFPLLEMGQIGIH--------HDSVVTKRLLSNCL 317
                                    |..|..|.|..:.....||        .:.::.:.||:...
E. coli   291 ------------------------PPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAY 331

  Fly   318 SGSRLKLATGYFNLTQEYM---DTLTHK-CLA-----QCSILMAHPNANGFQGAKGPAGGIPAAY 373
            |      |..|..:|..|.   |.|.|. |.|     ..||::...|.:...|
E. coli   332 S------AREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVG------------ 378

  Fly   374 TLIAKSFYESLVRRKQNHRVNFFEYEKPGWTYHAKGLWYYLPEAILPNLTLIGSSNFGERSVNRD 438
             ..:::|:..|:..    .|..:::|  |...|.|.:      .:...|:|:|:.|...||:  .
E. coli   379 -WASRAFFTELLAA----GVKIYQFE--GGLLHTKSV------LVDGELSLVGTVNLDMRSL--W 428

  Fly   439 LETQVCLVTANKDLSQRLQAEADRLYDLSQTAEREI-VQRPVPRWVQAVVRIFRNF 493
            |..::.|...:|.....|.|..|.....|:..:..: ::||:  |.:...|:|..|
E. coli   429 LNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPL--WQRVAERLFYFF 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGS1	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	32/180 (18%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	40/201 (20%)
clsA	NP_415765.1	cls	5..486	CDD:234967	94/511 (18%)