DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7718 and SPO14

DIOPT Version :9

Sequence 1:	NP_650751.3	Gene:	CG7718 / 42254	FlyBaseID:	FBgn0038649	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_012956.3	Gene:	SPO14 / 853902	SGDID:	S000001739	Length:	1683	Species:	Saccharomyces cerevisiae

Alignment Length:	257	Identity:	57/257 - (22%)
Similarity:	95/257 - (36%)	Gaps:	77/257 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IQVIHEPKHFY-----------------------ETLVQRIGQAK------RRIVLASLYLGTGQ 97
            :::|.:.:||.                       :.||.||.:|.      :..:|..|..|.
Yeast   964 LKLIEQSEHFIYIENQFFITSTVWNGTCVLNKIGDALVDRIVKANQEKKPWKAFILIPLMPGF-- 1026

  Fly    98 LENAMVQTLRHSLEQQSALRLNVLLDFTRGTRGTLNSKTMLLPLVRDFASQVQ---LSLYHT--P 157
              ::.|.|     .:.|:|||.:...:...:||..::.:.|..|..|.|..:|   |..:.|  |
Yeast  1027 --DSPVDT-----AEASSLRLIMQFQYQSISRGEHSTFSKLKKLNIDPAQYIQFFSLRKWSTFAP 1084

  Fly   158 DLRGMTKRLAPPRWNELLGLQHMKVYLFDD-AVIISGANLS-NDYFTNRQDRY-ILIEDKPLA-- 217
            :.|.:|::|          ..|.|:.:.|| ..||..||:: .....||.... |||.|..|.
Yeast  1085 NERLITEQL----------YVHAKILIADDRRCIIGSANINERSQLGNRDSEVAILIRDTDLIKT 1139

  Fly   218 -----DFYA-----QFIERVQEFSLAVAPDASEGLHRNWRILPYEGTKEQFIQLARKRISDL 269
                 |:||     :..:|:....|....|..|.:.:.:         |:|.:.|.|....|
Yeast  1140 KMNGDDYYAGKFPWELRQRLMREHLGCDVDLVEFVEKKF---------ERFEKFAAKNYEKL 1192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	48/213 (23%)
		PLDc_2	75..226	CDD:289836	45/176 (26%)
		PLDc_PGS1_euk_2	289..474	CDD:197235
SPO14	NP_012956.3	PX_domain	300..>390	CDD:413376
		PH_PLD	473..660	CDD:269956
		PLN02866	<638..1165	CDD:215467	49/219 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900