Protein Alignment PGS1 and PGS1

DIOPT Version :10

• Sequence 1: NP_650751.3
• Gene: PGS1 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_009923.2
• Gene: PGS1 / 850352
• SGDID: S000000510
• Length: 521
• Species: Saccharomyces cerevisiae
• Alignment Length: 512
• Identity: 160/512 - (31%)
• Similarity: 261/512 - (50%)
• Gaps: 69/512 - (13%)

  Fly    14 SPAAQGDFLGCLQQAPSVLATGFPGAPALESLSWLHNLAPCFPLRGDQIQVIHEPKHFYETLVQR 78
            :|:..|::|..:.:                  |...||..||..:..:|.:|..|..||:.|..:
Yeast    34 NPSPFGNYLNTITK------------------SLQQNLQTCFHFQAKEIDIIESPSQFYDLLKTK 80

  Fly    79 IGQAKRRIVLASLYLGTGQLENAMVQTLRHSLEQQSALRLNVLLDFTRGTR--GTLNSKTMLLPL 141
            |..::.||.:||||||..:.|  :|..:..:|.:...|:::.|||..||||  .:..|.|:|..|
Yeast    81 ILNSQNRIFIASLYLGKSETE--LVDCISQALTKNPKLKVSFLLDGLRGTRELPSACSATLLSSL 143

  Fly   142 VRDFASQ-VQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYLFDDAVIISGANLSNDYFTNRQ 205
            |..:.|: |...||.||...|..|.|.|.|:||.|||||||:|.||:.||:||||||||||||||
Yeast   144 VAKYGSERVDCRLYKTPAYHGWKKVLVPKRFNEGLGLQHMKIYGFDNEVILSGANLSNDYFTNRQ 208

  Fly   206 DRYILIEDKPLADFYAQFIERVQEFSLAVAPDASEG-LHRNWRILP-----YEGTKEQ--FIQLA 262
            |||.|.:.:..:::|.:..:.:..||..:.....:| ::..|   |     .|.||.:  |::.|
Yeast   209 DRYYLFKSRNFSNYYFKLHQLISSFSYQIIKPMVDGSINIIW---PDSNPTVEPTKNKRLFLREA 270

  Fly   263 RKRISDLVQETFQRQARTKEQNP-----QADTWIFPLLEMGQI-GIHHDSVVTKR--------LL 313
            .:.:...::.       :|:..|     |..|.::|:.:...: ..::|....||        :.
Yeast   271 SQLLDGFLKS-------SKQSLPITAVGQFSTLVYPISQFTPLFPKYNDKSTEKRTILSLLSTIT 328

  Fly   314 SNCLSGSRLKLATGYFNLTQEYMDTLTHKCLAQCSILMAHPNANGFQGAKGPAGGIPAAYTLIAK 378
            ||.:|.:   ...||||:..:....|....:|:.:::.|.|.||||..:||.:..:|.||..::|
Yeast   329 SNAISWT---FTAGYFNILPDIKAKLLATPVAEANVITASPFANGFYQSKGVSSNLPGAYLYLSK 390

  Fly   379 SFYESLVRRKQNHRVNFFEYE-----KP-GWTYHAKGLWYYLPEA-----ILPNLTLIGSSNFGE 432
            .|.:.:.|.:|:|.:...|::     || ||:|||||:|....:.     ..|.:|:|||||:..
Yeast   391 KFLQDVCRYRQDHAITLREWQRGVVNKPNGWSYHAKGIWLSARDKNDANNWKPFITVIGSSNYTR 455

  Fly   433 RSVNRDLETQVCLVTANKDLSQRLQAEADRLYDLSQTAEREIVQRPVPRWVQAVVRI 489
            |:.:.|||:...::|.:::|.::::||.|.|...::....|..|....|.|...|:|
Yeast   456 RAYSLDLESNALIITRDEELRKKMKAELDNLLQYTKPVTLEDFQSDPERHVGTGVKI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGS1	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	75/168 (45%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	58/204 (28%)
PGS1	NP_009923.2	PLDc_PGS1_euk_1	64..230	CDD:197233	78/168 (46%)
		PLDc_PGS1_euk_2	295..498	CDD:197235	63/227 (28%)