Protein Alignment CG7718 and PGS1

DIOPT Version :9

• Sequence 1: NP_650751.3
• Gene: CG7718 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_009923.2
• Gene: PGS1 / 850352
• SGDID: S000000510
• Length: 521
• Species: Saccharomyces cerevisiae
• Alignment Length: 512
• Identity: 160/512 - (31%)
• Similarity: 261/512 - (50%)
• Gaps: 69/512 - (13%)

  Fly    14 SPAAQGDFLGCLQQAPSVLATGFPGAPALESLSWLHNLAPCFPLRGDQIQVIHEPKHFYETLVQR 78
            :|:..|::|..:.:                  |...||..||..:..:|.:|..|..||:.|..:
Yeast    34 NPSPFGNYLNTITK------------------SLQQNLQTCFHFQAKEIDIIESPSQFYDLLKTK 80

  Fly    79 IGQAKRRIVLASLYLGTGQLENAMVQTLRHSLEQQSALRLNVLLDFTRGTR--GTLNSKTMLLPL 141
            |..::.||.:||||||..:.|  :|..:..:|.:...|:::.|||..||||  .:..|.|:|..|
Yeast    81 ILNSQNRIFIASLYLGKSETE--LVDCISQALTKNPKLKVSFLLDGLRGTRELPSACSATLLSSL 143

  Fly   142 VRDFASQ-VQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYLFDDAVIISGANLSNDYFTNRQ 205
            |..:.|: |...||.||...|..|.|.|.|:||.|||||||:|.||:.||:||||||||||||||
Yeast   144 VAKYGSERVDCRLYKTPAYHGWKKVLVPKRFNEGLGLQHMKIYGFDNEVILSGANLSNDYFTNRQ 208

  Fly   206 DRYILIEDKPLADFYAQFIERVQEFSLAVAPDASEG-LHRNWRILP-----YEGTKEQ--FIQLA 262
            |||.|.:.:..:::|.:..:.:..||..:.....:| ::..|   |     .|.||.:  |::.|
Yeast   209 DRYYLFKSRNFSNYYFKLHQLISSFSYQIIKPMVDGSINIIW---PDSNPTVEPTKNKRLFLREA 270

  Fly   263 RKRISDLVQETFQRQARTKEQNP-----QADTWIFPLLEMGQI-GIHHDSVVTKR--------LL 313
            .:.:...::.       :|:..|     |..|.::|:.:...: ..::|....||        :.
Yeast   271 SQLLDGFLKS-------SKQSLPITAVGQFSTLVYPISQFTPLFPKYNDKSTEKRTILSLLSTIT 328

  Fly   314 SNCLSGSRLKLATGYFNLTQEYMDTLTHKCLAQCSILMAHPNANGFQGAKGPAGGIPAAYTLIAK 378
            ||.:|.:   ...||||:..:....|....:|:.:::.|.|.||||..:||.:..:|.||..::|
Yeast   329 SNAISWT---FTAGYFNILPDIKAKLLATPVAEANVITASPFANGFYQSKGVSSNLPGAYLYLSK 390

  Fly   379 SFYESLVRRKQNHRVNFFEYE-----KP-GWTYHAKGLWYYLPEA-----ILPNLTLIGSSNFGE 432
            .|.:.:.|.:|:|.:...|::     || ||:|||||:|....:.     ..|.:|:|||||:..
Yeast   391 KFLQDVCRYRQDHAITLREWQRGVVNKPNGWSYHAKGIWLSARDKNDANNWKPFITVIGSSNYTR 455

  Fly   433 RSVNRDLETQVCLVTANKDLSQRLQAEADRLYDLSQTAEREIVQRPVPRWVQAVVRI 489
            |:.:.|||:...::|.:::|.::::||.|.|...::....|..|....|.|...|:|
Yeast   456 RAYSLDLESNALIITRDEELRKKMKAELDNLLQYTKPVTLEDFQSDPERHVGTGVKI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	75/168 (45%)
		PLDc_2	75..226	CDD:289836	70/153 (46%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	58/204 (28%)
PGS1	NP_009923.2	PLDc_PGS1_euk_1	64..230	CDD:197233	75/167 (45%)
		PLDc_PGS1_euk_2	295..498	CDD:197235	59/205 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344852
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5467
Inparanoid	1	1.050	233	1.000	Inparanoid score	I715
Isobase	1	0.950	-	0	Normalized mean entropy	S1652
OMA	1	1.010	-	-		QHG55277
OrthoFinder	1	1.000	-	-		FOG0005130
OrthoInspector	1	1.000	-	-		oto99509
orthoMCL	1	0.900	-	-		OOG6_102888
Panther	1	1.100	-	-	LDO	PTHR12586
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R916
SonicParanoid	1	1.000	-	-		X4150
TreeFam	1	0.960	-	-
	15	14.740