Protein Alignment CG7718 and Pgs1

DIOPT Version :9

• Sequence 1: NP_650751.3
• Gene: CG7718 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_598518.1
• Gene: Pgs1 / 74451
• MGIID: 1921701
• Length: 553
• Species: Mus musculus
• Alignment Length: 481
• Identity: 212/481 - (44%)
• Similarity: 297/481 - (61%)
• Gaps: 39/481 - (8%)

  Fly    47 WLHNLAPCFPLRGDQIQVIHEPKHFYETLVQRIGQAKRRIVLASLYLGTGQLENAMVQTLRHSLE 111
            |:.||.|.|.:....::|:..|..|:|.:..:|..||||:|:||||||||.||..:|..|..|||
Mouse    79 WIRNLVPEFGVSSSHVRVLSSPAEFFELMKGQIKIAKRRVVMASLYLGTGPLEQELVDCLESSLE 143

  Fly   112 QQ------SALRLNVLLDFTRGTRGTLNSKTMLLPLVRDFASQVQLSLYHTPDLRGMTKRLAPPR 170
            :.      |.|::::|||||||:||..||:||||||::.|..:|::||:|||:|||:.:.|.|.|
Mouse   144 KSLQAKFPSDLKVSILLDFTRGSRGRKNSRTMLLPLLQRFPERVRVSLFHTPNLRGLLRLLIPER 208

  Fly   171 WNELLGLQHMKVYLFDDAVIISGANLSNDYFTNRQDRYILIED-KPLADFYAQFIERVQEFSLAV 234
            :||.:||||:||||||:.||:||||||:.|||||||||:.::| ..:|||:.:.::.|.:.||.:
Mouse   209 FNETIGLQHIKVYLFDNNVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQL 273

  Fly   235 APDAS----EGLHRNWRILPYEGTKEQFIQLARKRISDLVQETFQRQ------------------ 277
            ..|.:    :|:     :.||:|.:..:.:.|.||:.|::.....||
Mouse   274 QGDDTVEVVDGM-----VHPYKGDRAAYCRAANKRVMDVIHSARARQQMLHAQTFHSDSLLSQEE 333

  Fly   278 -ARTKEQNPQADTWIFPLLEMGQIGIHHDSVVTKRLLSNCLSGSRLKLATGYFNLTQEYMDTLTH 341
             |...::.|..||||:||::|....|..|.:||:.||:....|:::.|.||||||||.||| |..
Mouse   334 AAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVFLTTGYFNLTQAYMD-LVL 397

  Fly   342 KCLAQCSILMAHPNANGFQGAKGPAGGIPAAYTLIAKSFYESLVRRKQNHRVNFFEYEKPGWTYH 406
            ...|:..||:|.|..|||.||||.||.|||||..|.:.||..:....|..||...||.:.|||:|
Mouse   398 GTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFYSEVCSLGQQDRVQLQEYWRRGWTFH 462

  Fly   407 AKGLWYYLPEAILPNLTLIGSSNFGERSVNRDLETQVCLVTANKDLSQRLQAEADRLYDLSQTAE 471
            |||||.||..:.||.||||||.|||.|||:||||.|:.:||.::.|.|:|..|.::||..|....
Mouse   463 AKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTESRSLQQQLHQEQEQLYLRSGVVT 527

  Fly   472 REIVQRP---VPRWVQAVVRIFRNFF 494
            ....::|   |..||:.|..:.:|||
Mouse   528 SATFEQPGRQVKLWVKMVTPLIKNFF 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	90/172 (52%)
		PLDc_2	75..226	CDD:289836	86/157 (55%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	92/184 (50%)
Pgs1	NP_598518.1	PLDc_PGS1_euk_1	93..266	CDD:197233	90/172 (52%)
		PLDc_PGS1_euk_2	346..505	CDD:197235	85/159 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842750
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5467
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1993
Isobase	1	0.950	-	0	Normalized mean entropy	S1652
OMA	1	1.010	-	-		QHG55277
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005130
OrthoInspector	1	1.000	-	-		oto93277
orthoMCL	1	0.900	-	-		OOG6_102888
Panther	1	1.100	-	-	LDO	PTHR12586
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R916
SonicParanoid	1	1.000	-	-		X4150
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.740