DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7718 and Pld6

DIOPT Version :9

Sequence 1:	NP_650751.3	Gene:	CG7718 / 42254	FlyBaseID:	FBgn0038649	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_220517.1	Gene:	Pld6 / 287366	RGDID:	1311987	Length:	222	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	54/224 - (24%)
Similarity:	88/224 - (39%)	Gaps:	52/224 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VLATGFPGAPALESLSWLHN--LAPCFPLRGDQIQVIHEPKHF--YETLVQRIGQAKRRIVLASL 91
            |.|.|...|.|||:|.||..  ||...|.|    :|:..|...  .|.|:|..|
  Rat     9 VFAAGAGLALALEALPWLMRWLLAGRRPRR----EVLFFPSQVTCTEALLQAPG----------- 58

  Fly    92 YLGTG----------QLENAMVQTLRHSLEQQSALRLNVLLDFTRGTRG----TLNSKTMLLPLV 142
             |..|          ..|:::.:.||..|..:|:|.| .|..|:....|    .|:.:.:.:.::
  Rat    59 -LPPGPSSGCPCSLPHSESSLSRLLRALLAARSSLEL-CLFAFSSPQLGRAVQLLHQRGVRVRVI 121

  Fly   143 RDF------ASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYLFDDAVIISGA-NLSNDY 200
            .|.      .||:.|          :.|.....|.::.||..|.|..:.|..|:|:|: |.:...
  Rat   122 TDCDYMALNGSQIGL----------LRKAGIQVRHDQDLGYMHHKFAIVDKKVLITGSLNWTTQA 176

  Fly   201 FTNRQDRYILIEDKPLADFYAQFIERVQE 229
            ..|.::..:::||......:.:..||:.|
  Rat   177 IQNNRENVLIMEDTEYVRLFLEEFERIWE 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	38/188 (20%)
		PLDc_2	75..226	CDD:289836	34/171 (20%)
		PLDc_PGS1_euk_2	289..474	CDD:197235
Pld6	XP_220517.1	PLDc_vPLD6_like	93..204	CDD:197268	25/121 (21%)
Pld6	XP_220517.1	PLDc_2	94..204	CDD:289836	25/120 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900