DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PGS1 and Pld6

DIOPT Version :10

Sequence 1:NP_650751.3 Gene:PGS1 / 42254 FlyBaseID:FBgn0038649 Length:494 Species:Drosophila melanogaster
Sequence 2:NP_001277212.1 Gene:Pld6 / 194908 MGIID:2687283 Length:221 Species:Mus musculus


Alignment Length:223 Identity:54/223 - (24%)
Similarity:88/223 - (39%) Gaps:51/223 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 VLATGFPGAPALESLSWLHN--LAPCFPLRGDQIQVIHEPKHF--YETLVQRIGQAKRRIVLASL 91
            |.|.|...|.|||:|.||..  ||...|.|    :|:..|...  .|.|:|..|           
Mouse     9 VFAAGAGLALALEALPWLMRWLLAGRRPRR----EVLFFPSQVTCTEALLQAPG----------- 58

  Fly    92 YLGTG---------QLENAMVQTLRHSLEQQSALRLNVLLDFTRGTRG----TLNSKTMLLPLVR 143
             |..|         ..|:::.:.||..|..:|:|.| .|..|:....|    .|:.:.:.:.::.
Mouse    59 -LPPGPSGCPCSLPHSESSLSRLLRALLAARSSLEL-CLFAFSSPQLGRAVQLLHQRGVRVRVIT 121

  Fly   144 DF------ASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYLFDDAVIISGA-NLSNDYF 201
            |.      .||:.|          :.|.....|.::.||..|.|..:.|..|:|:|: |.:....
Mouse   122 DCDYMALNGSQIGL----------LRKAGIQVRHDQDLGYMHHKFAIVDKKVLITGSLNWTTQAI 176

  Fly   202 TNRQDRYILIEDKPLADFYAQFIERVQE 229
            .|.::..:::||......:.:..||:.|
Mouse   177 QNNRENVLIMEDTEYVRLFLEEFERIWE 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PGS1NP_650751.3 PLDc_PGS1_euk_1 61..227 CDD:197233 38/187 (20%)
PLDc_PGS1_euk_2 289..474 CDD:197235
Pld6NP_001277212.1 Required for mitochondrial localization 1..38 13/28 (46%)
PLDc_vPLD6_like 92..203 CDD:197268 25/121 (21%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.