Protein Alignment PGS1 and Pld2

DIOPT Version :10

• Sequence 1: NP_650751.3
• Gene: PGS1 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001289404.1
• Gene: Pld2 / 18806
• MGIID: 892877
• Length: 944
• Species: Mus musculus
• Alignment Length: 567
• Identity: 110/567 - (19%)
• Similarity: 182/567 - (32%)
• Gaps: 192/567 - (33%)

  Fly     7 RLFSQELSPAAQG---DFLGCLQQAPSVLATGFPGAPALESLSWLHNLAPCFPLRGDQIQVIHEP 68
            |.:.||::..|||   |||. |.|..| .|...||..|    .|..|.|..|....|.|.
Mouse   300 RWWGQEITELAQGSGRDFLQ-LHQHDS-YAPPRPGTLA----RWFVNGAGYFAAVADAIL----- 353

  Fly    69 KHFYETLVQRIGQAKRRIVLASLYLGTGQLENAMVQTLRHS----------LEQQSALRLNVLL- 122
                        :|:..|.:...:|.    ....::...||          .:.:..:|:::||
Mouse   354 ------------RAQEEIFITDWWLS----PEIYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLF 402

  Fly   123 ---DFTRGTRGTLNSKTMLLPLVRDFASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKVYL 184
               :...|.....:.:|::|       ....:.:...|||             ..|...|.|:.:
Mouse   403 KEVELALGINSGYSKRTLML-------LHPNIKVMRHPDL-------------VTLWAHHEKLLV 447

  Fly   185 FDDAV-IISGANLSNDYFTNRQDRYILIED--KPLADFYAQFIERVQEFSLAVAPDASEGLHRN- 245
            .|..| .:.|.:|:...:.:.|.|...:.|  :|:         .:|..:|...|.|:..|..|
Mouse   448 VDQVVAFLGGLDLAFGRWDDVQYRLTDLGDPSEPV---------HLQTPTLGSDPAATPDLSHNQ 503

  Fly   246 --WRILPYEG--TKEQFIQLARK-------------------------RISDLVQETFQRQARTK 281
              |....|..  ||: ::||.|.                         ...||.:...||...||
Mouse   504 FFWLGKDYSNLITKD-WVQLDRPFEDFIDRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTK 567

  Fly   282 EQNPQADTWIFP---------------LLEMGQIGIHHDSVVTKRLLSNCLSGS-RLKLATGYFN 330
            ....:..|.::|               ::..||..    :|...|.:....:|: ...:...|.:
Mouse   568 TTKARYKTPLYPYLLPKSTSTANNLPFMIPGGQCA----TVQVLRSVDRWSAGTLENSILNAYLH 628

  Fly   331 LTQEYMDTL--THKCLAQCS----------------ILMAH------------PNANGFQGAKGP 365
            ..:|....|  .::....||                ||.||            |...||:|....
Mouse   629 TIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHEQGQCFRVYLLLPLLPGFEGDIST 693

  Fly   366 AGG------IPAAYTL-IAKSFY--ESLVRRKQN--HRVN------FFEY----------EKPGW 403
            .||      :...|:| :...|:  .:|.|.:.:  ||:.      :.:|          |..|
Mouse   694 GGGNSIQAILHFTYSLCLLHPFFSLRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGG- 757

  Fly   404 TYHAKGLWYYLPEAIL---PNLTLIGSSNFGERSV--NRDLETQVCL 445
              |......|:...:|   ....:|||:|..:||:  .||.|..:.:
Mouse   758 --HPISELIYIHSKMLIADDRTVIIGSANINDRSLLGKRDSELAILI 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGS1	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	26/182 (14%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	44/235 (19%)
Pld2	NP_001289404.1	PLN02866	67..929	CDD:215467	110/567 (19%)