Protein Alignment CG7718 and Pld1

DIOPT Version :9

• Sequence 1: NP_650751.3
• Gene: CG7718 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001355596.1
• Gene: Pld1 / 18805
• MGIID: 109585
• Length: 1074
• Species: Mus musculus
• Alignment Length: 586
• Identity: 119/586 - (20%)
• Similarity: 193/586 - (32%)
• Gaps: 195/586 - (33%)

  Fly    22 LGCLQQAPSVLATGFPGAPALESLSWL-----HNLAPCFPLRGDQIQVIHEPKHFYETLVQRIGQ 81
            :|.:::..|.|:.|...|.::||:..|     |......|:.    :::.|.    :..::.||:
Mouse   497 VGSVKRVTSGLSLGSLTAASVESMESLSLKDKHEFHKKEPIS----KIVDET----DMKLKGIGK 553

  Fly    82 AKRRIVLASLYLGTGQLENAMVQTLRHSLEQQSALRLNVLLDFTRGTRGTLNSKTMLLPLVRDFA 146
            : |:....|||.          |..||.|....::.   .:|.|........|...|:     ..
Mouse   554 S-RKFSKFSLYR----------QLHRHHLHNADSIS---SIDSTSSYFSHCRSHQNLI-----HG 599

  Fly   147 SQVQLSLYH--TPDLRGMTK--------RLAPPRWNELLG---LQHMKVY---LFDDAVIISGAN 195
            .:..|.|:|  :...:|:|:        |.......||.|   ..|.|.|   :|.|.|.:
Mouse   600 LKPHLKLFHPSSESEQGLTRHSTDTGSIRSVQTGVGELHGETRFWHGKDYCNFVFKDWVQL---- 660

  Fly   196 LSNDYFTNRQDRYILIEDKPLADFYAQFIERVQEFSLAVAP--DASEGLHRNWRILPYEGTKEQF 258
                             |||.|||       :..:|....|  |....:|
Mouse   661 -----------------DKPFADF-------IDRYSTPRMPWHDIGSVVH--------------- 686

  Fly   259 IQLARKRISDLVQETFQRQARTKEQNPQADTWIFP-LLEMGQIGIHH------DSVVTK-RLLSN 315
                .|...|:.:...||...||...|:..:..:| ||...|...|.      .:|..| :||.:
Mouse   687 ----GKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQATAHELRYQVPGAVPAKVQLLRS 747

  Fly   316 CLSGS------RLKLATGYFNLTQ--EYMDTLTHKCLAQCS----------------ILMAH--- 353
            ....|      ...:...|.::.:  ::...:.::....|:                ||.||
Mouse   748 AADWSAGIKHHEESIHAAYIHVIENSKHYIYIENQFFISCADDKVVFNKVGDAIAQRILKAHREG 812

  Fly   354 ---------PNANGFQGAKGPAGG------IPAAYTLIAK---SFYESLVRRKQNHRVNFFEYEK 400
                     |...||:|.....||      :...|..:.:   |..|.|.....|..:|:..:
Mouse   813 QRYRVYIVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGESSILEQLKPELGNKWINYISF-- 875

  Fly   401 PGWTYHAK-------GLWYYLPEAIL--PNLTLIGSSNFGERSV--NRDLETQVCL--------V 446
            .|...||:       .|.|...:.::  .|..:|||:|..:||:  .||.|..|.:        |
Mouse   876 CGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSV 940

  Fly   447 TANKD-----LSQRLQAEADRL---YDLSQTAEREIVQRPVPR------WVQAVVR-------IF 490
            ...|:     .::.|:.|..||   | ||..:|.  :|.||..      ||....|       :|
Mouse   941 MDGKEYQAGRFARDLRLECFRLVLGY-LSDPSED--LQDPVSDKFFKEIWVSTAARNATIYDKVF 1002

  Fly   491 R 491
            |
Mouse  1003 R 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	36/181 (20%)
		PLDc_2	75..226	CDD:289836	35/166 (21%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	54/264 (20%)
Pld1	NP_001355596.1	PLN02866	82..1059	CDD:215467	119/586 (20%)
		Catalytic	463..928		100/506 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900