Protein Alignment CG7718 and pgs-1

DIOPT Version :9

• Sequence 1: NP_650751.3
• Gene: CG7718 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_490666.2
• Gene: pgs-1 / 171594
• WormBaseID: WBGene00021677
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 174/454 - (38%)
• Similarity: 267/454 - (58%)
• Gaps: 30/454 - (6%)

  Fly    53 PCFPLRGDQIQVIHEPKHFYETLVQRIGQAKRRIVLASLYLGTGQLENAMVQTLRHSLEQQSALR 117
            |..|:....::::..|..|||.|::.....:||:.|.|||||.|.||..::..:|...| :|.:.
 Worm     9 PGIPIDPQDLEILDTPTRFYEKLLELTASTERRLALCSLYLGEGDLEKNLIAAIRERSE-KSEIE 72

  Fly   118 LNVLLDFTRGTRGTLNSKTMLLPLVRDFASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKV 182
            :.:||||.|||| |.:|....:.:::..:.:.::.|:|||:|.|:.||:.|.|.:|::||||||:
 Worm    73 VTILLDFLRGTR-TNSSGESSVTVLKPISEKSKIYLFHTPELSGLVKRVLPQRADEIIGLQHMKL 136

  Fly   183 YLFDDAVIISGANLSNDYFTNRQDRYILIED-KPLADFYAQFIERVQEFSLAV-----APDASEG 241
            |:|||.|:|||||||:.|||||.|||.|..: ||||||:.:.|..|.:.|..|     .|.....
 Worm   137 YIFDDNVLISGANLSDSYFTNRTDRYFLFRNCKPLADFFHEIINVVADSSFIVENEQLVPSPKCD 201

  Fly   242 LHRNWRILPYEGTKEQFIQLARKRISDLVQETFQRQARTKEQNPQADTWIFPLLEMGQIGIHHDS 306
            :|      ||.|:...:.::.:.|::.:: |.::...:|......|||||:|:|:||.:|||.:.
 Worm   202 VH------PYLGSAHLYREMLKTRVNRVI-EKYKESRKTSSNCMSADTWIYPVLQMGLLGIHQEF 259

  Fly   307 VVTKRLLSNCLSGSRLK--LATGYFNLTQEYMDTLTHKCLAQCSILMAHPNANGFQGAKGPAGGI 369
            ...::|.|  |....||  :|:||||..::|.:::..:......||.|.|.||||..:.|.:..|
 Worm   260 EFLQKLFS--LKNPELKMTMASGYFNFIRDYEESILKEGDYHLDILTASPFANGFFESNGFSKYI 322

  Fly   370 PAAYTLIAKSFYESLVRRKQNHRVN--FFEYEKPGWTYHAKGLWYYLPEAILPNLTLIGSSNFGE 432
            |..|:.|:..|   |.:|:.|.|:|  .|||.:..||:||||||   .|.....:|||||||:|.
 Worm   323 PPLYSNISDQF---LRKREINGRLNVKMFEYRREEWTFHAKGLW---AEHNNQLMTLIGSSNYGY 381

  Fly   433 RSVNRDLETQVCLVTANKDLSQRLQAEADRLYDLSQTAEREIVQRP---VPRWVQAVVRIFRNF 493
            |||:||||.||.:||.|..|..||:.|.:.|::.|...:...:|:|   :|..|:.:.|:.|:|
 Worm   382 RSVHRDLEAQVMVVTRNPTLIDRLKDEKNLLFEYSSILDMAALQQPEHHIPPLVRVISRLIRSF 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7718	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	74/166 (45%)
		PLDc_2	75..226	CDD:289836	70/151 (46%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	78/188 (41%)
pgs-1	NP_490666.2	PLDc_PGS1_euk_1	17..182	CDD:197233	74/166 (45%)
		PLDc_PGS1_euk_2	242..417	CDD:197235	77/182 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5467
Inparanoid	1	1.050	294	1.000	Inparanoid score	I1673
Isobase	1	0.950	-	0	Normalized mean entropy	S1652
OMA	1	1.010	-	-		QHG55277
OrthoDB	1	1.010	-	-		D1358866at2759
OrthoFinder	1	1.000	-	-		FOG0005130
OrthoInspector	1	1.000	-	-		oto17580
orthoMCL	1	0.900	-	-		OOG6_102888
Panther	1	1.100	-	-	LDO	PTHR12586
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R916
SonicParanoid	1	1.000	-	-		X4150
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750