Protein Alignment PGS1 and pgs-1

DIOPT Version :10

• Sequence 1: NP_650751.3
• Gene: PGS1 / 42254
• FlyBaseID: FBgn0038649
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_490666.2
• Gene: pgs-1 / 171594
• WormBaseID: WBGene00021677
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 174/454 - (38%)
• Similarity: 267/454 - (58%)
• Gaps: 30/454 - (6%)

  Fly    53 PCFPLRGDQIQVIHEPKHFYETLVQRIGQAKRRIVLASLYLGTGQLENAMVQTLRHSLEQQSALR 117
            |..|:....::::..|..|||.|::.....:||:.|.|||||.|.||..::..:|...| :|.:.
 Worm     9 PGIPIDPQDLEILDTPTRFYEKLLELTASTERRLALCSLYLGEGDLEKNLIAAIRERSE-KSEIE 72

  Fly   118 LNVLLDFTRGTRGTLNSKTMLLPLVRDFASQVQLSLYHTPDLRGMTKRLAPPRWNELLGLQHMKV 182
            :.:||||.|||| |.:|....:.:::..:.:.::.|:|||:|.|:.||:.|.|.:|::||||||:
 Worm    73 VTILLDFLRGTR-TNSSGESSVTVLKPISEKSKIYLFHTPELSGLVKRVLPQRADEIIGLQHMKL 136

  Fly   183 YLFDDAVIISGANLSNDYFTNRQDRYILIED-KPLADFYAQFIERVQEFSLAV-----APDASEG 241
            |:|||.|:|||||||:.|||||.|||.|..: ||||||:.:.|..|.:.|..|     .|.....
 Worm   137 YIFDDNVLISGANLSDSYFTNRTDRYFLFRNCKPLADFFHEIINVVADSSFIVENEQLVPSPKCD 201

  Fly   242 LHRNWRILPYEGTKEQFIQLARKRISDLVQETFQRQARTKEQNPQADTWIFPLLEMGQIGIHHDS 306
            :|      ||.|:...:.::.:.|::.:: |.::...:|......|||||:|:|:||.:|||.:.
 Worm   202 VH------PYLGSAHLYREMLKTRVNRVI-EKYKESRKTSSNCMSADTWIYPVLQMGLLGIHQEF 259

  Fly   307 VVTKRLLSNCLSGSRLK--LATGYFNLTQEYMDTLTHKCLAQCSILMAHPNANGFQGAKGPAGGI 369
            ...::|.|  |....||  :|:||||..::|.:::..:......||.|.|.||||..:.|.:..|
 Worm   260 EFLQKLFS--LKNPELKMTMASGYFNFIRDYEESILKEGDYHLDILTASPFANGFFESNGFSKYI 322

  Fly   370 PAAYTLIAKSFYESLVRRKQNHRVN--FFEYEKPGWTYHAKGLWYYLPEAILPNLTLIGSSNFGE 432
            |..|:.|:..|   |.:|:.|.|:|  .|||.:..||:||||||   .|.....:|||||||:|.
 Worm   323 PPLYSNISDQF---LRKREINGRLNVKMFEYRREEWTFHAKGLW---AEHNNQLMTLIGSSNYGY 381

  Fly   433 RSVNRDLETQVCLVTANKDLSQRLQAEADRLYDLSQTAEREIVQRP---VPRWVQAVVRIFRNF 493
            |||:||||.||.:||.|..|..||:.|.:.|::.|...:...:|:|   :|..|:.:.|:.|:|
 Worm   382 RSVHRDLEAQVMVVTRNPTLIDRLKDEKNLLFEYSSILDMAALQQPEHHIPPLVRVISRLIRSF 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGS1	NP_650751.3	PLDc_PGS1_euk_1	61..227	CDD:197233	74/166 (45%)
		PLDc_PGS1_euk_2	289..474	CDD:197235	78/188 (41%)
pgs-1	NP_490666.2	PLDc_PGS1_euk_1	17..182	CDD:197233	74/166 (45%)
		PLDc_PGS1_euk_2	242..417	CDD:197235	77/182 (42%)