Protein Alignment Mekk1 and KIC1

DIOPT Version :10

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_011970.1
• Gene: KIC1 / 856502
• SGDID: S000001144
• Length: 1080
• Species: Saccharomyces cerevisiae
• Alignment Length: 263
• Identity: 89/263 - (33%)
• Similarity: 138/263 - (52%)
• Gaps: 21/263 - (7%)

  Fly  1288 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKH-KNLVRYYGIEVHR 1351
            ||:|:||.||...|..||.:.|:|.:.:. .::..:::|..|::.|..:|. .|:.||||..:..
Yeast    29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLD-SDSDEVEDVQREIQFLASLKQISNITRYYGSYLKD 92

  Fly  1352 EELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGS 1416
            ..|.|.||.|:.|:|.||:. .|.:.|........:||..:..:||..::|||||.||: |:...
Yeast    93 TSLWIIMEHCAGGSLRSLLR-PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANV-LITNE 155

  Fly  1417 NSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG--HGRAADIWSVGCVVVEM 1479
            .::||.|||.|.::. .|::  ..|...||..:|||||.    .:|  :....||||:|....|:
Yeast   156 GNVKLCDFGVAAQVN-QTSL--RRQTMAGTPYWMAPEVI----MEGVYYDTKVDIWSLGITTYEI 213

  Fly  1480 ASGKRPWAQFDS--NFQIMFKVGMGEKPQAPE--SLSQEGHDFIDHCLQHDPKRRLTAVELLEHN 1540
            |:|..|:...::  ..|::.|    .||...|  |.|....:||..||..|||.||:|.:||:..
Yeast   214 ATGNPPYCDVEALRAMQLIIK----SKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSK 274

  Fly  1541 FCK 1543
            |.:
Yeast   275 FIR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	88/260 (34%)
KIC1	NP_011970.1	STKc_NAK1_like	21..295	CDD:270822	89/263 (34%)