Protein Alignment Mekk1 and MKK2

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_015185.1
• Gene: MKK2 / 855963
• SGDID: S000006061
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 112/477 - (23%)
• Similarity: 187/477 - (39%)
• Gaps: 104/477 - (21%)

  Fly  1127 SPRTRKTSSPAT--SRSRTPTRTPMSAGMVL------------NPNTPPLQSPPYNKLLHPQFSL 1177
            ||.:....||.:  |.|.|.|.:.|::...|            .|..|||          |...|
Yeast    42 SPYSSVNESPYSNNSTSATSTTSSMASNSTLLYNRSSTTTIKNRPVPPPL----------PPLVL 96

  Fly  1178 KEDVSGTSYSPVDSSDYVDTPCQRSANGELRLLVPQTPPTPASPGKSSLESTPLALRQERVRDAV 1242
            .:...|..|.....|..    .:|.:|..:.:..           |..|.|.|::.:...:....
Yeast    97 TQKKDGIEYRVAGDSQL----SERFSNLHVDITY-----------KELLSSAPISTKLSNIDTTF 146

  Fly  1243 NRLDMDL---EDGLRERRLIGQVKSLNSSDKVHIRARSV----------------HFRWHRG-IK 1287
            .:.|:|.   ||......|.....|.:.|:...:.|.::                ...|..| :|
Yeast   147 IKKDLDTPEGEDSYPSTLLSAYDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLK 211

  Fly  1288 --------IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 1344
                    :|:|..|.|......|..::.|:|.|.....:....|.:..||:..:..|...:|:|
Yeast   212 DEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQY 276

  Fly  1345 YGI--EVHREELLIFMELCS----EGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHR 1403
            ||:  :.....:.|.||...    |.|.::|::..|.:.|.:..:....:|.|:|.||:..::||
Yeast   277 YGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHR 341

  Fly  1404 DIKTANIFLVDGSNSLKLGDF---GSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 1465
            |||..|| |::....:||.||   |.||...|.|        :.||..|||||   :.....:..
Yeast   342 DIKPQNI-LLNEKGEIKLCDFGVSGEAVNSLAMT--------FTGTSFYMAPE---RIQGQPYSV 394

  Fly  1466 AADIWSVGCVVVEMASGKRPWAQFDSN-------------FQIMFKVGMGEKPQAPESLSQEGHD 1517
            ..|:||:|..::|:|.|:.|   |:|:             ..:.|...:.::|:...|.|:....
Yeast   395 TCDVWSLGLTLLEVAGGRFP---FESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRS 456

  Fly  1518 FIDHCLQHDPKRRLTAVELLEH 1539
            |||:||:.|.:.|.:..::|:|
Yeast   457 FIDYCLKKDARERPSPRQMLKH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	79/290 (27%)
		S_TKc	1282..1541	CDD:214567	79/289 (27%)
MKK2	NP_015185.1	PKc_Pek1_like	212..499	CDD:270793	76/282 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840