Protein Alignment Mekk1 and CDC15

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_009411.2
• Gene: CDC15 / 851274
• SGDID: S000000072
• Length: 974
• Species: Saccharomyces cerevisiae
• Alignment Length: 310
• Identity: 96/310 - (30%)
• Similarity: 160/310 - (51%)
• Gaps: 27/310 - (8%)

  Fly  1262 VKSLNSSDKVHI----RARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA 1322
            :.|:..:|:|::    ||.....::|....||:|.:|.||.|:|.:|.:::|:||:..:..|  .
Yeast     1 MNSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDE--E 63

  Fly  1323 LKNVAEELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTG-NLPEALTRRFTA 1386
            |.::..|:.:|:.:.|.|:|:|:|......||.|.:|.|:.|:|..|:..:. .|.|..::.:..
Yeast    64 LNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVT 128

  Fly  1387 QLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMA 1451
            |.|.|:..||..|::|||||.||| |:...|::||.|||      ..|.|........||..:||
Yeast   129 QTLLGLKYLHGEGVIHRDIKAANI-LLSADNTVKLADFG------VSTIVNSSALTLAGTLNWMA 186

  Fly  1452 PEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQF-DSNFQIMFKVGMGEKPQAPESLSQEG 1515
            ||:.   .:.|....:||||:|..||||.:...|:... |:|  |.:.| ..:....|.|.|:..
Yeast   187 PEIL---GNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDAN--IYYAV-ENDTYYPPSSFSEPL 245

  Fly  1516 HDFIDHCLQHDPKRRLTAVELLEHNFCKYGRDECSSEQLQMQVRGSFRRN 1565
            .||:..|...:..:|.||.:||:|.:..      |:|.:::.....|:.:
Yeast   246 KDFLSKCFVKNMYKRPTADQLLKHVWIN------STENVKVDKLNKFKED 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	88/262 (34%)
		S_TKc	1282..1541	CDD:214567	88/260 (34%)
CDC15	NP_009411.2	PKc_like	24..272	CDD:419665	88/262 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002637
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910