DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mekk1 and NP3

DIOPT Version :9

Sequence 1:	NP_732373.1	Gene:	Mekk1 / 42253	FlyBaseID:	FBgn0024329	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	NP_187254.1	Gene:	NP3 / 819774	AraportID:	AT3G06030	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	336	Identity:	128/336 - (38%)
Similarity:	181/336 - (53%)	Gaps:	35/336 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1239 RDAVNRLDMDLEDGLRERRLIGQVKSLNSSDKVHIRARSV-------------------HFRWHR 1284
            |..|.|..:..:||.....|.|.|..:|||    ||:..:                   ..||.:
plant    10 RSLVFRSSLAGDDGTSGGGLSGFVGKINSS----IRSSRIGLFSKPPPGLPAPRKEEAPSIRWRK 70

  Fly  1285 GIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA------LKNVAEELKILEGIKHKNLVR 1343
            |..||.|.||:||..:|.::|||:|:|::.|.|.....      ::.:.||:::|:.:.|.|:||
plant    71 GELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVR 135

  Fly  1344 YYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTA 1408
            |.|.....:.|.|.||....|::.||:|..|:.||.:...:|.|||.|:..||.:||:|||||.|
plant   136 YLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGA 200

  Fly  1409 NIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVG 1473
            || |||....::|.|||::.|:....||.| .:...||..:|||||..:|   ||..:|||||||
plant   201 NI-LVDNKGCIRLADFGASKKVVELATVNG-AKSMKGTPYWMAPEVILQT---GHSFSADIWSVG 260

  Fly  1474 CVVVEMASGKRPWAQFDSNFQIMFKVGMGE-KPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELL 1537
            |.|:|||:||.||::....|..:..:|..: .|..||.||.|..||:..||..:|..||:|.|||
plant   261 CTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELL 325

  Fly  1538 EHNFCKYGRDE 1548
            :|.|....|.|
plant   326 QHPFVTGKRQE 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	112/267 (42%)
Mekk1	NP_732373.1	S_TKc	1282..1541	CDD:214567	111/265 (42%)
NP3	NP_187254.1	STKc_MAPKKK	67..330	CDD:270783	112/267 (42%)
NP3	NP_187254.1	S_TKc	68..330	CDD:214567	111/266 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	209	1.000	Domainoid score	I802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2506
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910