Protein Alignment Mekk1 and Stk3

DIOPT Version :10

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_038935793.1
• Gene: Stk3 / 65189
• RGDID: 68412
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 95/355 - (26%)
• Similarity: 157/355 - (44%)
• Gaps: 64/355 - (18%)

  Fly  1213 QTPPTPASPGKSSLESTPLALRQERVRDAVNRLDMDLEDGLRERRLIGQVKSLNSSDKVHIRARS 1277
            :.||.|.|..| .|....|..:.|.|.|.:.
  Rat     2 EQPPAPKSKLK-KLSEDSLTKQPEEVFDVLE---------------------------------- 31

  Fly  1278 VHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLV 1342
                     |:|:|.:|.|:.|::..:|:::|:|::.::..    |:.:.:|:.|::......:|
  Rat    32 ---------KLGEGSYGSVFKAIHKESGQVVAIKQVPVESD----LQEIIKEISIMQQCDSPYVV 83

  Fly  1343 RYYGIEVHREELLIFMELCSEGTLESLVELTG-NLPEALTRRFTAQLLSGVSELHKHGIVHRDIK 1406
            :|||......:|.|.||.|..|::..::.|.. .|.|..........|.|:..||....:|||||
  Rat    84 KYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIK 148

  Fly  1407 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWS 1471
            ..|| |::.....||.|||.|.::   |....:....:||..:|||||..:.   |:...|||||
  Rat   149 AGNI-LLNTEGHAKLADFGVAGQL---TDTMAKRNTVIGTPFWMAPEVIQEI---GYNCVADIWS 206

  Fly  1472 VGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKP--QAPESLSQEGHDFIDHCLQHDPKRRLTAV 1534
            :|...:|||.||.|:|.... .:.:|.:.....|  :.||..|.:..||:..||...|::|.||.
  Rat   207 LGITSIEMAEGKPPYADIHP-MRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATAT 270

  Fly  1535 ELLEHNFCKYGRD-----ECSSEQLQMQVR 1559
            :||:|.|.|..:.     |..:|.::::.:
  Rat   271 QLLQHPFIKNAKPVSILRELITEGMEIKAK 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	81/263 (31%)
Stk3	XP_038935793.1	STKc_MST1_2	23..278	CDD:132943	84/309 (27%)
		Mst1_SARAH	481..525	CDD:463314