Protein Alignment Mekk1 and slkb

DIOPT Version :10

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_001315314.1
• Gene: slkb / 562769
• ZFINID: ZDB-GENE-030131-1684
• Length: 969
• Species: Danio rerio
• Alignment Length: 292
• Identity: 91/292 - (31%)
• Similarity: 143/292 - (48%)
• Gaps: 21/292 - (7%)

  Fly  1259 IGQVKSLNSSDKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA- 1322
            :|..|.....|.|| |..:....|....::|.|.||||:.|.|..||...|.|.|     :|:.
Zfish    12 LGIEKKKKQYDHVH-RDTNPEEIWEIVGELGDGAFGKVFKAQNKQTGIFAAAKVI-----DTKTE 70

  Fly  1323 --LKNVAEELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLES-LVELTGNLPEALTRRF 1384
              |::...|:.||....|.|:|:.........:|.|.:|.|:.|.::: ::||...|.|...|..
Zfish    71 DELEDYMVEIDILASCDHHNIVKLLDAFYFESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVV 135

  Fly  1385 TAQLLSGVSELHKHGIVHRDIKTANIFL-VDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQA 1448
            ..|.|..:..||.:.::|||:|..||.| :||  .:||.|||.:.|   :|........::||..
Zfish   136 CKQTLDALLYLHDNKVIHRDLKAGNILLTLDG--DVKLADFGVSAK---NTKTVQRRDSFIGTPY 195

  Fly  1449 YMAPE-VFTKTNSD-GHGRAADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQ--APE 1509
            :|||| |..:|:.| .:...|||||:|..::|:|..:.|..:.:. .:::.|:...|.|.  .|.
Zfish   196 WMAPEVVMCETSKDRPYDYKADIWSLGITLIELAQIEPPNHEMNP-MRVLLKIAKAEPPTLLQPS 259

  Fly  1510 SLSQEGHDFIDHCLQHDPKRRLTAVELLEHNF 1541
            ..|.|..||:.|.|:.:...|.:..:||:|.|
Zfish   260 KWSPEFRDFLKHALEKNVDNRWSTAQLLQHPF 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	85/270 (31%)
slkb	NP_001315314.1	Protein Kinases, catalytic domain	29..310	CDD:473864	85/274 (31%)
		PKK	616..723	CDD:463600
		PKK	753..894	CDD:463600