Protein Alignment Mekk1 and map3k2

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_686613.2
• Gene: map3k2 / 558321
• ZFINID: ZDB-GENE-120215-96
• Length: 623
• Species: Danio rerio
• Alignment Length: 640
• Identity: 167/640 - (26%)
• Similarity: 268/640 - (41%)
• Gaps: 123/640 - (19%)

  Fly   930 ETTDFHREHYEHDVANQQHDFICSDVKAAFKLLQQDVLQVRNKLTAIIEGVQKRCCLSNMRDLDE 994
            ::.|.|..:.|..:.....|    |:..|.:||.:.|.....|:..::....:.|..|
Zfish    77 QSMDLHYTNNELVIPLSTQD----DLDKAVELLDRSVHMKSLKILLVLPSWSQNCVSS------- 130

  Fly   995 QDKQAVLSRTREILHQGYKFGFEYHKDVIRLFEQKIMDQKDSGAHTVDLALGIIAYAKMWMHFVM 1059
                                     ||::...:  |:|..|..|..         ...|..|...
Zfish   131 -------------------------KDLLPTHD--ILDNTDFSAPD---------KKSMLAHIGS 159

  Fly  1060 ERCERGRGMRPRWASQGLEFLILACDPQITQHLDDDEFEALKQQMDRCISHVIGITSEPEKVAKK 1124
            :..:|. ...|.:....|:  .:|.:...|....:.||  :.:.||:.:..:  ..|.||    .
Zfish   160 QSTDRS-SPPPGYIPDALQ--QVARNGSFTSINSEGEF--IPESMDQMLDPL--SMSSPE----N 213

  Fly  1125 KASPRTRKTSSPATSRSRTPTRTPMSAGMVLNPNTPPLQSPPYNKLLHPQFSL----KEDVSGT- 1184
            .||.......||..|.:...:|.|.:.            |.|.|....|::.:    |....||
Zfish   214 SASGSCPSLDSPLDSDTYPKSRMPRAL------------SYPDNHQEFPEYDIPVFEKTGKGGTY 266

  Fly  1185 ---SYSPVDSSDYVD-----TPCQRSANGELRLLVPQTPPTPASPGKSSLES--TPLALRQERVR 1239
               .:.|....||.|     ...:|:.....|..|..:|....||..||..|  ||
Zfish   267 PRRYHIPFGLQDYSDGRKTFPRARRTQAHGFRSPVSFSPTEQQSPSTSSGSSIFTP--------- 322

  Fly  1240 DAVNRLDMDLEDGLRERRLIGQVKSLNSSDKVHI-------RARSVHFRWHRGIKIGQGRFGKVY 1297
                    :||:..|.||  |.....:|:..:.:       |:......|..|..:|||.||:|:
Zfish   323 --------ELEEPGRRRR--GSDIEPSSNPTLSVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVF 377

  Fly  1298 TAVNNNTGELMAMKEIAIQPGETRALKNVAE---ELKILEGIKHKNLVRYYGI--EVHREELLIF 1357
            ...:.:||..:|:|::...|......|.|:.   |:::|:.:.|:.:|:|||.  :.|.:.|.||
Zfish   378 LCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHEKTLSIF 442

  Fly  1358 MELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLG 1422
            ||....|:::..::..|.|.|.:||::|.|:|.||..||.:.|||||||.||| |.|.:.::|||
Zfish   443 MEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANI-LRDSAGNVKLG 506

  Fly  1423 DFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWA 1487
            |||::.::|........::...||..:|:|||.   :.:|:||.|||||:||.||||.:.:.|||
Zfish   507 DFGASRRLQTICLSGTGIKSVTGTPYWMSPEVI---SGEGYGRKADIWSIGCTVVEMLTQRPPWA 568

  Fly  1488 QFDSNFQIMFKVG-MGEKPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNF 1541
            :|:: ...:||:. ....|..|..:|....||:..... :.|:|..|.:||.|.|
Zfish   569 EFEA-MAAIFKIATQPTNPTLPPHVSDHCRDFLKRIFV-ETKQRPAAEDLLRHTF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	98/267 (37%)
		S_TKc	1282..1541	CDD:214567	97/264 (37%)
map3k2	XP_686613.2	PB1_Mekk2_3	43..121	CDD:99726	10/47 (21%)
		STKc_MEKK2	359..622	CDD:270818	98/269 (36%)
		S_TKc	362..622	CDD:214567	98/266 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D55144at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920