DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mekk1 and map4k5

DIOPT Version :9

Sequence 1:NP_732373.1 Gene:Mekk1 / 42253 FlyBaseID:FBgn0024329 Length:1571 Species:Drosophila melanogaster
Sequence 2:XP_021336201.1 Gene:map4k5 / 334565 ZFINID:ZDB-GENE-030131-6497 Length:894 Species:Danio rerio


Alignment Length:269 Identity:94/269 - (34%)
Similarity:141/269 - (52%) Gaps:31/269 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly  1287 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGIEVHR 1351
            ::|.|.:|.||.|...:||||.|:|.|.::||:..::  :.:|:.:::...|.|:|.|:|..:.|
Zfish    25 RVGSGTYGDVYKARKISTGELAAVKIIKLEPGDDFSI--IQQEIFMVKECTHHNIVAYFGSYLCR 87

  Fly  1352 EELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGS 1416
            |:|.|.||.|..|:|:.:..:||.|.|........:.|.|:..||..|.:|||||.|||.|.| :
Zfish    88 EKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLGYLHSKGKMHRDIKGANILLTD-N 151

  Fly  1417 NSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMAS 1481
            ..:||.|||.|.||   |....:.:.::||..:|||||.....:.|:....|||:||...:|:|.
Zfish   152 GDVKLADFGVAAKI---TATMAKRKSFIGTPYWMAPEVAAVEKNGGYNHLCDIWAVGITSIELAE 213

  Fly  1482 GKRPWAQFD------------SNFQIMFKVGMGEKPQAPESL--SQEGHDFIDHCLQHDPKRRLT 1532
            .:.|  .||            ||||         .|:..:..  |...|:|:...|..:||||.|
Zfish   214 LQPP--MFDLHPMRALFLMSKSNFQ---------PPKLKDKTKWSTAFHNFVKLSLTKNPKRRPT 267

  Fly  1533 AVELLEHNF 1541
            |.::|.|.|
Zfish   268 AEKMLSHLF 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mekk1NP_732373.1 STKc_MEKK4 1281..1542 CDD:270796 94/269 (35%)
S_TKc 1282..1541 CDD:214567 93/267 (35%)
map4k5XP_021336201.1 STKc_MAP4K5 10..277 CDD:270813 94/269 (35%)
CNH 559..874 CDD:214481
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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