Protein Alignment Mekk1 and Stk10

DIOPT Version :10

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_062079.2
• Gene: Stk10 / 29398
• RGDID: 3779
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 83/264 - (31%)
• Similarity: 138/264 - (52%)
• Gaps: 20/264 - (7%)

  Fly  1287 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA---LKNVAEELKILEGIKHKNLVRYYGIE 1348
            ::|.|.|||||.|.|..||.|.|.|.|     ||::   |::...|::||....|..:|:..|..
  Rat    41 ELGDGAFGKVYKAKNKETGALAAAKVI-----ETKSEEELEDYIVEIEILATCDHPYIVKLLGAY 100

  Fly  1349 VHREELLIFMELCSEGTLES-LVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFL 1412
            .:..:|.|.:|.|..|.::: ::||...|.|...:....|:|..::.||...|:|||:|..|:.:
  Rat   101 YYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLM 165

  Fly  1413 -VDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPE-VFTKTNSDG-HGRAADIWSVGC 1474
             ::|  .::|.|||.:.|   :.....:...::||..:|||| |..:|..|. :...|||||:|.
  Rat   166 TLEG--DIRLADFGVSAK---NLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGI 225

  Fly  1475 VVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQ--APESLSQEGHDFIDHCLQHDPKRRLTAVELL 1537
            .::|||..:.|..:.:. .:::.|:...:.|.  .|...|.|..||:...|..:|:.|.:|.:||
  Rat   226 TLIEMAQIEPPHHELNP-MRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQLL 289

  Fly  1538 EHNF 1541
            :|.|
  Rat   290 QHPF 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	83/264 (31%)
Stk10	NP_062079.2	STKc_STK10	23..314	CDD:132975	83/264 (31%)
		PKK	600..738	CDD:463600
		PKK	768..908	CDD:463600