Protein Alignment Mekk1 and pak2a

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_001002717.1
• Gene: pak2a / 266749
• ZFINID: ZDB-GENE-021011-2
• Length: 517
• Species: Danio rerio
• Alignment Length: 501
• Identity: 127/501 - (25%)
• Similarity: 219/501 - (43%)
• Gaps: 84/501 - (16%)

  Fly  1085 DPQITQHLDDD----EFEALKQQMDRCISHVIGITSEPEKVAKKK-------------ASPRTRK 1132
            |.:.|.|:..|    ||..:.:|..|.:.     ||...|..:||             ::..:|:
Zfish    80 DFEHTIHVGFDSVTGEFTGMPEQWARLLQ-----TSNITKSEQKKNPQAVLDVLKFYDSTGNSRQ 139

  Fly  1133 TSSPATSRSRTPTRTPMSAGMVLNPNTPPLQSPPYNKLLHPQFSLKEDVSGTSYSPVDSSDYVDT 1197
            .....|.:.....:.......|.:|:.....:||......||.:    :|..:.|.:|
Zfish   140 KYLSFTDKDAPQAKKGSEQSPVKDPDDDDEDAPPPVVAPRPQHT----ISVYTRSVID------- 193

  Fly  1198 PCQRSANGELRLLVPQTPPTPASPGKSSLESTPLALRQERVRDAVNRLDMDLEDGLRERRLIGQV 1262
                              |.||....:..:.:..|.:|::.:..:.  |.::.:.||....||..
Zfish   194 ------------------PIPAPAAIADTDGSKAADKQKKGKGKMT--DEEIMEKLRTIVSIGDP 238

  Fly  1263 KSLNSSDKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVA 1327
            |.                ::.|..|||||..|.||||::..||:.:|:|:|.:|....:.|  :.
Zfish   239 KK----------------KYTRYEKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKEL--II 285

  Fly  1328 EELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGV 1392
            .|:.:::.:|:.|:|.:....:..:||.:.||..:.|:|..:|..| .:.||.......:.|..:
Zfish   286 NEILVMKELKNPNIVNFLDSFLVGDELFVVMEYLAGGSLTDVVTET-CMDEAQIAAVCRECLQAL 349

  Fly  1393 SELHKHGIVHRDIKTANIFL-VDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFT 1456
            ..||.:.::|||||:.|:.| :||  |:||.|||...:|   |....:....|||..:|||||.|
Zfish   350 EFLHANQVIHRDIKSDNVLLGMDG--SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVT 409

  Fly  1457 KTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKP--QAPESLSQEGHDFI 1519
            :   ..:|...||||:|.:.:||..|:.|:.. ::..:.::.:.....|  |.||.||....||:
Zfish   410 R---KAYGPKVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTPELQNPEKLSPIFRDFL 470

  Fly  1520 DHCLQHDPKRRLTAVELLEHNFCKYGRDECSSEQLQMQVRGSFRRN 1565
            :.||:.|.::|....|||:|.|.|..:...|...|.:..:.:.:.|
Zfish   471 NRCLEMDVEKRGGGKELLQHPFLKLAKPLSSLTPLILAAKEAMKSN 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	87/263 (33%)
		S_TKc	1282..1541	CDD:214567	87/261 (33%)
pak2a	NP_001002717.1	PBD	74..129	CDD:279166	13/53 (25%)
		STKc_PAK2	222..517	CDD:132986	98/323 (30%)
		S_TKc	242..493	CDD:214567	87/262 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910