Protein Alignment Mekk1 and mbt

DIOPT Version :10

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_061515451.1
• Gene: mbt / 1271082
• VectorBaseID: AGAMI1_006890
• Length: 837
• Species: Anopheles gambiae
• Alignment Length: 674
• Identity: 149/674 - (22%)
• Similarity: 238/674 - (35%)
• Gaps: 169/674 - (25%)

  Fly  1001 LSRTREILHQGYKFGFEYHKDVIRLFEQKIMDQKDSGAHTVDLALGIIAYAKMWMHFVMERCERG 1065
            :|.|..:|...:...||.|...::..:|:.|.|.                 :|.||.:.::.::.
Mosquito   182 VSPTGTMLETNFNNNFEAHHQQLQQQQQQQMAQH-----------------QMHMHHMQQQQQQQ 229

  Fly  1066 R---GMRPRWASQGLEFLILACDPQITQHLDDDEFEALKQQMDRCISHVIGITSEPEKVAKKKAS 1127
            :   .|.|..|......:..|....|..|::...............|:  |..:.|..|..:.:|
Mosquito   230 QQHHHMHPHQAGAVGGNVQAAAGHAIAPHMNGGNLSNAASLNGTTGSN--GNLTNPVSVLTETSS 292

  Fly  1128 ---PRTRKTS--------SPATSRSRTPTRTPMSAGMVLNPNT--------------PPLQSPPY 1167
               .|::|:|        .|....:..|...||.||     |:              |||.|.|.
Mosquito   293 LYHNRSQKSSPTGSDGMQRPGGYPNAAPYPGPMQAG-----NSFPGMAQGAGGGGPPPPLHSKPQ 352

  Fly  1168 NKLLHP--QFSLKED--------------------------------------VSGTSYSP---- 1188
            .: .||  |...::|                                      .||:..||
Mosquito   353 GQ-NHPGQQQQQQQDPHGHLSDANNGNHLPPGHHHHHHHHQMMGVQGGNTGSQPSGSQLSPSGLH 416

  Fly  1189 -----------------VDSSDYVDTPCQRSANGEL---------RLLVPQTPPTPASPGKSSLE 1227
                             ........||.|...|.::         ..:|......| ||..||..
Mosquito   417 HHHQHAHHHGAQQQQQQQQQQQMQPTPLQMGGNNQMPNHHHHHNHNAMVHNHQKMP-SPSSSSST 480

  Fly  1228 STPLALRQERVRDAVNRLDMDLEDGLRERRLIGQVKSLNSS-------------DKVHIRARSVH 1279
            ..|..........:.|....:.:...|.....|...|:..|             ..|....|..|
Mosquito   481 GAPTVATDPNHMFSNNNSISNAKSNSRASSSSGGNVSVAQSTASTTQSGQSQQQPPVKTEQRLTH 545

  Fly  1280 FRWHRGI-----------------KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVA 1327
            .::...:                 |||:|..|.|..|.:.:||..:|:|::.::..:.|.|  :.
Mosquito   546 EQFRAALQMVVSAGDPRENLENYTKIGEGSTGTVCIATDKSTGRQVAVKQMDLRKQQRREL--LF 608

  Fly  1328 EELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGV 1392
            .|:.|:....|.|:|..|...:..:||.:.||....|.|..:| ....:.|........|.|..:
Mosquito   609 NEVVIMRDYHHPNIVETYSSFLVNDELWVVMEFLEGGALTDIV-TNSRMDEEQIATVCKQCLKAL 672

  Fly  1393 SELHKHGIVHRDIKTANIFLV-DGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFT 1456
            |.||..|::|||||:.:|.|. ||  .:||.|||...::...  :| :.:..|||..:|:|||.:
Mosquito   673 SYLHSQGVIHRDIKSDSILLASDG--RVKLSDFGFCAQVSQE--LP-KRKSLVGTPYWMSPEVIS 732

  Fly  1457 KTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPES--LSQEGHDFI 1519
            :.   .:|...||||:|.:|:||..|:.|:.. :...|.|.::.....|:...|  :|....:|:
Mosquito   733 RL---PYGPEVDIWSLGIMVIEMIDGEPPFFN-EPPLQAMRRIRDMPPPKLKNSHKVSSRLQNFL 793

  Fly  1520 DHCLQHDPKRRLTAVELLEHNFCK 1543
            |..|..||.:|.||.|||.|.|.:
Mosquito   794 DRMLVRDPVQRATAAELLAHPFLR 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	83/280 (30%)
mbt	XP_061515451.1	None