Protein Alignment Mekk1 and map3k22

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_002938051.2
• Gene: map3k22 / 100488360
• XenbaseID: XB-GENE-990946
• Length: 618
• Species: Xenopus tropicalis
• Alignment Length: 699
• Identity: 176/699 - (25%)
• Similarity: 289/699 - (41%)
• Gaps: 192/699 - (27%)

  Fly   954 DVKAAFKLLQQDVLQVRNKLTAIIEGVQKRCCLSNMRDLDEQDKQAVLSRTREILHQGYKFGFEY 1018
            |.:.|.:|:.:| |....|...:::|..::.|       .:||.:             .||.:..
 Frog     2 DEEEALQLIMKD-LAALGKCGGLLDGHHRKIC-------KQQDAR-------------IKFEYNG 45

  Fly  1019 HKDVI---RLFEQKIMDQK--DSGAHTVDLALGIIAYAKMWMHFVMERCERGRGMRPRWASQGLE 1078
            .|.:|   |..:.|.:.||  |:...|:||            |:..:                 |
 Frog    46 EKRIIEFRRPIKLKDVQQKVTDAFGQTMDL------------HYAND-----------------E 81

  Fly  1079 FLI-LACDPQITQHLDDDEFEALKQQMDRC--ISHVIGITSEPEKVAKKKASPRTRKTSSPATSR 1140
            .|| |.|        .:|..:|| :.:|.|  :..:..:...|:|....:|...|.:...|...:
 Frog    82 LLIPLTC--------QEDMDKAL-EYLDACPALKSLKILVKAPKKNIVSRAPEATMRYLQPVCPK 137

  Fly  1141 SRTPTRTPMSAGMVLNP-----------NTPPL----QSPPYNKLLHPQFSLKEDVSGTSYSPVD 1190
            .. ..|...|.|.:|..           :|..|    .|||...:...|..:....|.||.
 Frog   138 PH-DMRISKSMGDILGSLYKDADKTRKFSTGSLHTGRSSPPPGSVPDEQQQIARQGSYTSI---- 197

  Fly  1191 SSDYVDTPCQRSANGELRLLVPQTPPTPASPGKS----------SLE----STPLALRQERVRDA 1241
                       ::.||   .:|:......||.:|          ||:    |||:...:.::.|:
 Frog   198 -----------NSEGE---FIPEVIDPFISPNESLSSSCQSLDRSLDSPAFSTPVPRGKGQLNDS 248

  Fly  1242 VNRLDM-----------------------DLEDGLR--ERRLI----------GQVKSLN----- 1266
            ::.||.                       |..||.|  .|..|          .:.:|:|
 Frog   249 LDCLDFEIPFYERFGKGGTFPRQYHFSRKDYNDGRRTFPRSYIPPENIFPLSSSRTRSVNGESGL 313

  Fly  1267 -------------------------SSDKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGE 1306
                                     :|.:.:.::......|..|..:|:|.||:||...:.:.|.
 Frog   314 VPMSCDEQRKKRWNSSEQGFPFFCSTSQEQNNKSPQAPENWRLGKLLGRGAFGEVYLCYDVDKGR 378

  Fly  1307 LMAMKEIAIQPG--ETRALKNVAE-ELKILEGIKHKNLVRYYGI--EVHREELLIFMELCSEGTL 1366
            .:|:|::...|.  ||....|..| |:::|:..:|:.:|:|||.  :....:|.||:|....|::
 Frog   379 ELAVKQVPFDPDSQETSKEVNALECEIQLLKLHRHERIVQYYGCLRDPTERKLSIFVEYMPGGSI 443

  Fly  1367 ESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQ 1431
            :..::..|.|.|.:|||:|.|:|.|||.||.:.|||||||.||| |.|.:.::||||||::.:||
 Frog   444 KDQLKAYGALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANI-LRDSAGNVKLGDFGASKRIQ 507

  Fly  1432 AHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDSNFQIM 1496
            ........::...||..:|:|||.   :.:|:||.||:|||.|.||||.:.|.||::::: ...:
 Frog   508 TICMSGTGIKSVTGTPYWMSPEVI---SGEGYGRKADVWSVACTVVEMLTEKPPWSEYEA-MAAI 568

  Fly  1497 FKVG-MGEKPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKY 1544
            ||:. ...||:.|:::|....||:......: |||.||.|||.|.|..:
 Frog   569 FKIATQPTKPRLPDTVSDACRDFMKQIFVEE-KRRPTAEELLRHLFVSH 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	101/266 (38%)
		S_TKc	1282..1541	CDD:214567	101/264 (38%)
map3k22	XP_002938051.2	PB1_Mekk2_3	37..115	CDD:99726	23/128 (18%)
		STKc_MEKK3_like_u1	351..614	CDD:270819	101/268 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D55144at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010