Protein Alignment Mekk1 and si:ch211-1i11.3

DIOPT Version :9

• Sequence 1: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_009290786.1
• Gene: si:ch211-1i11.3 / 100005496
• ZFINID: ZDB-GENE-030131-8638
• Length: 1324
• Species: Danio rerio
• Alignment Length: 1137
• Identity: 236/1137 - (20%)
• Similarity: 407/1137 - (35%)
• Gaps: 370/1137 - (32%)

  Fly   546 GSASRKGVTPCHKVQFMLNDATHVPGETSSSNESTST-EVSQWSSECSHSH--MRKGSMHDINIF 607
            |.|.:..::|..:.:.:  ...::..|..|..::..| .:...:..|:.:|  ::..|...|.:.
Zfish    37 GGAGKNVISPRSRTRAL--SVVYIAVEDGSLPQTEETLSLKCLTEACADAHAVLKSISYERIALG 99

  Fly   608 SVEPLGTCSSNGTGEQSTGLYRKFIENVLKSRGLAKSLAFLH--------KLHNVALYKAHIALE 664
            :.|.|.|            .|...:..|..:..:.:...|.|        ..:||.||
Zfish   100 TTEILDT------------FYNADVVVVEMNNSICQPSLFYHLGVRESFSMTNNVILY------- 145

  Fly   665 KPGAEDFDYESDAESIEEDVPRLDPEISREQVVELRTYGYWSEEAQSINLPSYIPTFVFLSG--- 726
                        ....|:|:          |||:.:...|           ::||..|...|
Zfish   146 ------------CNKQEDDM----------QVVKEQCGSY-----------TFIPYMVSPQGKVF 177

  Fly   727 -------------IPLQFMHEFLRMRLETRPVR----PNPLSLEQLMKELREGLTLALTH----- 769
                         :...|..|.|...|..|.|:    .:..|.|.|.:.:|..:.||..|
Zfish   178 ACDAALMRAVKDFLHSSFKFESLMTSLVDRLVKLLESVHINSSEYLHEAIRREIRLAREHFTGPA 242

  Fly   770 --RE--RYQRH----------ITTALVENEAELGSYISILNHYDATVRKTFELYLEYIDQLVLVA 820
              :|  |.|:.          |..:|:.:..::..|.||:|            .:|.::.|.:..
Zfish   243 LSQELGRIQKRLDSVELLSPDIVMSLLLSYRDIPDYDSIIN------------LVETLNNLPMCM 295

  Fly   821 VPEGNQKSVLEKEWMFT--------------KLISPMIKGMHTLASQKFCGIISKLLRSISERLV 871
            ||....   ::.:::|.              |||.|:::...|:||..:|         :..|:.
Zfish   296 VPAHQN---IKFQYIFALNRRNHPGDRVRALKLILPIVESGETVASDVYC---------LCGRIY 348

  Fly   872 KRTVELDQQI-DGTADTDDNEEV-KWQLLTICRETQSLLTVERERSIKVLFFAKTFCRDVETTDF 934
            |     |..: .|..||:..::. ||                         :.|.|..:...
Zfish   349 K-----DMFLSSGFKDTNSRDQASKW-------------------------YGKAFTIEPSL--- 380

  Fly   935 HREHYEHDVANQ-------QHDFICSDVKAAFKLLQQDVLQVRNKLTAIIEGVQKRCCLSNMRDL 992
                  |...|.       .|:|..|             :::|.....:...:.::..|..|:|.
Zfish   381 ------HSGINNVVLLMAAGHEFDTS-------------IELRKIGVTLSSLLGRKGSLEKMQDY 426

  Fly   993 DEQDKQAVLSRTREILHQGYKFGF--------EYHKDVI----RLFEQKIMDQKDSGAHTVDLAL 1045
                               :..||        ..||.||    ||:..|
Zfish   427 -------------------WDVGFYLGAGILANEHKKVIDASERLYRLK---------------- 456

  Fly  1046 GIIAYAKMW-------MHFVMERCERGRGM---RPRWASQGLEFLILACDPQITQHLDDDEFEAL 1100
                 |.||       .:.:.::..:.|.:   :...|...:|.::.||.|.::
Zfish   457 -----APMWYVASIMETYILYKQFAKPREVNHPKQETADFWMELMVQACKPTVS----------- 505

  Fly  1101 KQQMDRCISHVIGITSEPEKVAKKKASPRTRKTSSPATSRSRTPTRTPMSAGMVLNPNTPPLQSP 1165
               ..||...::    ||.||.:    |.....|....||:            |...:..||:
Zfish   506 ---TARCPVLIL----EPTKVFQ----PSIISVSEEDDSRT------------VQLRHVTPLE-- 545

  Fly  1166 PYNKLLHPQFSLKEDVSGTSYSPVDSSDYVDTPCQRSA-------NGELRLLVPQTPPTPASPGK 1223
               |.||........:.|.|.|..|         :||.       :.:.:|..|
Zfish   546 ---KGLHEWTFPASAIRGVSISKFD---------ERSCFLYVLYNSDDFQLYFP----------- 587

  Fly  1224 SSLESTPLALRQERVRDAVNRLDMDLEDGLRERRLIGQVKSL----NSSDKVHIRARSVHFRWHR 1284
            |.|......   :.|...:::.:..:||....|...|.::.:    .:.|||
Zfish   588 SDLHCKGFC---DLVNSLLHQTESPVEDSSSMRGEEGDLEYIYERNENGDKV------------- 636

  Fly  1285 GIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGIEV 1349
              .:|:|.:|.||...:.:....:|:|||..:  ::...:.:.||:.:.:.:||:|:|:|.|...
Zfish   637 --VLGKGTYGVVYAGRDLSNQVRIAIKEIPEK--DSTYSQPLHEEIALHKRLKHRNIVQYLGSVS 697

  Fly  1350 HREELLIFMELCSEGTLESLVE-----LTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTAN 1409
            ....:.||||....|:|.||:.     |..|  ||....:|.|:|.|:..||.:.|||||||..|
Zfish   698 EDGFIKIFMEEVPGGSLSSLLRSKWGPLKDN--EATIVFYTKQILDGLKYLHDNQIVHRDIKGDN 760

  Fly  1410 IFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGC 1474
            :.:...|..||:.|||::.::..   :....:.:.||..|||||:..: ...|:|:.|||||:||
Zfish   761 VLVNTYSGVLKISDFGTSKRLAG---INPCTETFTGTLQYMAPEIIDQ-GPRGYGKPADIWSLGC 821

  Fly  1475 VVVEMASGKRPWAQFDSNFQIMFKVGMGE-KPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLE 1538
            .::|||:||.|:.:..|....||||||.: .|..||.:|::..|||..|.:.:|.:|.||.|||:
Zfish   822 TIIEMATGKPPFHELGSPQAAMFKVGMFKIHPAVPECMSEQAKDFIMCCFEPNPDKRTTASELLK 886

  Fly  1539 HNFCKYG---RDECSSEQLQMQVRGSFRRNVA 1567
            :.|.|..   |.:..::....:..|.|.|:::
Zfish   887 NGFLKASAKKRLKPLADNSLKEPAGEFHRSMS 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mekk1	NP_732373.1	STKc_MEKK4	1281..1542	CDD:270796	93/266 (35%)
		S_TKc	1282..1541	CDD:214567	93/264 (35%)
si:ch211-1i11.3	XP_009290786.1	DUF4071	126..494	CDD:290020	84/523 (16%)
		STKc_ASK	623..890	CDD:270794	96/289 (33%)
		S_TKc	637..890	CDD:214567	93/260 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D55144at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920