Protein Alignment ChAT and YAT1

DIOPT Version :9

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_009420.1
• Gene: YAT1 / 851285
• SGDID: S000000080
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 702
• Identity: 182/702 - (25%)
• Similarity: 290/702 - (41%)
• Gaps: 143/702 - (20%)

  Fly    88 LPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGA--RLHQYLL--DKREAED 148
            |.::|:|.|.:|:..|:..:||:....|..||:   |...:.:.:.|  .||:.||  |.|.||.
Yeast     4 LKRLPIPPLQDTLNRYLARVEPLQDERQNRRTR---RTVLSAENLDALNTLHERLLEYDARLAES 65

  Fly   149 N----WAYYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDV----------AHF-----AAR 194
            |    :...:|. :.|:.....:.:|.||  .|..:...|:.|.          ||.     |||
Yeast    66 NPESSYIEQFWY-DAYLLYDATVVLNVNP--YFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAAR 127

  Fly   195 LLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYRLLGSCR-RPGVKQDSQFLPSRERLNDE 258
            |...||.....:..|.|   |..:.....||.|.||.||.||.| .||..:.|..|    :.:..
Yeast   128 LTTSILKFIRQIRHGTL---RTDTVRGKTPLSMDQYERLFGSSRIPPGPGEPSCHL----QTDAT 185

  Fly   259 DRHVVVICRNQMYCV-VLQASDRGKLSESEIASQILY-VLSDAPCLPAKPVPVGLLTAEPRSTWA 321
            ..|||.:.|.|.|.. ||...:....:..|.....|| ::.||....:...|.|:.|.|.|..|:
Yeast   186 SHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWS 250

  Fly   322 RDREML--QEDERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEM 384
            ..|:.|  .:|..|.|||:||::|..|:|||:                ....|..:||  :...|
Yeast   251 NIRDYLFHADDCTNWRNLKLIDSALFVVCLDD----------------VAFAADQQDE--LTRSM 297

  Fly   385 IHGGGS------------EYNSG---NRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKI 434
            :.|..:            ...:|   |||:|| :|||:..:|..|:.:||:..:|..|::|...|
Yeast   298 LCGTSTINLDPHQHQPPLNVQTGTCLNRWYDK-LQLIVTKNGKAGINFEHTGVDGHTVLRLATDI 361

  Fly   435 Y------------KKIEEHPDEDNGLPQ-----------HHLPPPERLEWHVGPQLQLRFAQASK 476
            |            |.:.:...:|:|.|.           :.:..|.:|||.....||.....|..
Yeast   362 YTDSILSFARGVTKNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFLQSSLHFAET 426

  Fly   477 SVDKCIDDLDFYVYRYQSYGKTFIKSC-QVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLH 540
            .:...|...:|....:.:||.:.||:. :.|||.::|...|:|::.||||....||.|.|:.|.:
Yeast   427 RISDLISQYEFVNLDFSNYGASHIKTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQN 491

  Fly   541 GRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQT 605
            ||.:.||:.:.::..:.|::..            :|..::.|:           :|...|....:
Yeast   492 GRTEAIRSVTGQSKLFVKSLLD------------QDASDATKI-----------QLLHDACTAHS 533

  Fly   606 EVMVKNILGNGIDIPLLGL--------REASIEVTGEMHELFKDESYIISQCFLLSTSQVACSTD 662
            ::..:...|.|.|..|..|        ::..     |:..:|:|:|:...|..:||||.......
Yeast   534 QITRECSQGLGQDRHLYALYCLWNQWYKDKL-----ELPPIFRDKSWTTMQNNVLSTSNCGNPCL 593

  Fly   663 SFMGYGPVTPRGYGCSY--NPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSL 712
            ...|:||||..|:|..|  ..|      .||...|......:|:|..::.||
Yeast   594 KSFGFGPVTANGFGIGYIIRDH------SVSVVVSSRHRQTARFASLMEKSL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	182/702 (26%)
YAT1	NP_009420.1	Carn_acyltransf	4..642	CDD:395612	182/702 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910