Protein Alignment ChAT and CPT2

DIOPT Version :10

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 182/715 - (25%)
• Similarity: 307/715 - (42%)
• Gaps: 132/715 - (18%)

  Fly    72 WLSTAES-----------------VDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERT 119
            |:||..|                 :....|..:||::|:|.|:.:...::.|.:|:.:||:..:|
  Fly    12 WISTNSSRTTTTHGQHYQYLQCSKLPTLYFQRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQT 76

  Fly   120 KELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYY---WLNEMYMDIRIPLPINSNPGMVF---- 177
            ::.:.||.  ||||..||. .|...:||:....|.   |. :||:..|.|||:|.||.:|.
  Fly    77 QQTVEQFR--QGIGMELHA-KLKSHDAENKHTSYISQPWF-DMYLADRAPLPLNYNPLLVMKSDA 137

  Fly   178 -PPRRFKTVH----------------------DVAHFAARLLDGILSHREMLDSGELPLERAASR 219
             |..:.:.|.                      :|.|..|:..|.....|.|..:.:.....|:..
  Fly   138 RPEYQQQVVRATNLIISSLRFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYA 202

  Fly   220 EKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDED-RHVVVICRNQMYCV-VLQASDRGK 282
            .|..||.|:||.||.|:.|.|.:.:|       |.:...| :|::|:.|..||.| ||.:|  |.
  Fly   203 FKAFPLDMSQYNRLFGTSRIPRIGKD-------ELVQSPDAKHILVMRRGHMYAVNVLDSS--GY 258

  Fly   283 L-SESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDERNQRNLEL-IETAQV 345
            : |.|.|..::..||.......|..||:|:||:..|..||:.|:....:.:|...||. ::.|..
  Fly   259 IESPSVILGRLRAVLKLDADREAASVPLGVLTSGQRDEWAKTRQHFVSNTKNADLLEREVDAALF 323

  Fly   346 VLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTD 410
            .:|||....|.||.              ::.|..:.| ::.|     .:.||||||::.|:|..|
  Fly   324 CVCLDGEEDGVFNE--------------NQQEPLLKH-LLAG-----KAQNRWFDKSISLLISAD 368

  Fly   411 GTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHP-------------DEDNGLPQHHLPPPERLEWH 462
            ||..:.:|||..:|:||::...::||...:.|             |..|..|         :.:.
  Fly   369 GTTAINFEHSWGDGVAVLRYFNELYKDTLKQPFVSTETVHTPAEGDFSNVRP---------INFE 424

  Fly   463 VGPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLV 527
            :....:...::|.......:|:||..|.:|....|...|...:|||..|||:.|||:.:.|...|
  Fly   425 IDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYRQAYSGYV 489

  Fly   528 ATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDH 592
            .:|||.||..|.|||.:.:|..:....::.:|:.|.|.:..                    |...
  Fly   490 GSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKP--------------------SAGE 534

  Fly   593 LRELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQV 657
            ||.:.........::..:..:|.|.|..|..||..:.:....:.:|::.|:|......::|||.:
  Fly   535 LRAMIDNCSKVHGQLTKEAAMGQGFDRHLFALRHTAQKEGIPIPDLYETEAYKRINNNIISTSTL 599

  Fly   658 ACSTDSFM--GYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLLQ 720
              .:|:.:  .:|||...|:|..|:...:.....|:.:.:..|...  :..||:.:.|.:..::|
  Fly   600 --GSDALLAGSFGPVVKNGFGIGYSIQNDFAGAIVTTYKNQADGKV--FIDSLESAFDKICAVIQ 660

  Fly   721  720
              Fly   661  660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	92..710	CDD:459926	173/666 (26%)
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	173/667 (26%)