Protein Alignment ChAT and cpt-3

DIOPT Version :9

• Sequence 1: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_497498.2
• Gene: cpt-3 / 190055
• WormBaseID: WBGene00021703
• Length: 722
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 170/717 - (23%)
• Similarity: 297/717 - (41%)
• Gaps: 153/717 - (21%)

  Fly    51 LSNITPSDTGWKDSILSIPKKWLSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQ 115
            ||::.|......|.:||                      .:|:|.|::|:..|..:::.:.:..:
 Worm   113 LSHVAPPQLSSCDRLLS----------------------NLPLPRLEDTVTRYTDSMKFVISEEE 155

  Fly   116 LERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSN--PGMVFP 178
            .........||.:.:|...:...:||  ....||:..::|...:|...|.||||.|:  ..:::.
 Worm   156 HNNLIATSTQFLSHEGRTLQRFAWLL--HLITDNYVTWFWEKYIYYAGRYPLPIISSTCQCVLYG 218

  Fly   179 PRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYR-LLGSCRRPGV 242
            ......|:.|    ||||     :.|.|  ..|.::|.........|...::|| :....|.||.
 Worm   219 EDDLTQVYQV----ARLL-----YIETL--ANLSVDRQDYLAVGDGLMSTRHYRNIYNGSRVPGA 272

  Fly   243 KQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPV 307
            :.|:      .:.|...||.:|:.:...|.|.....|....|.:|:|.    ::|:......|..
 Worm   273 EIDN------FQWNPPSRHALVVHKGTWYKVDTCDEDGRLYSVNELAK----IVSELTTRQDKST 327

  Fly   308 ----PVGLLTAEPRSTWARD-REMLQEDERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATP 367
                .:..|||:.|:.|::: |:....:..|::.||:|||:|.|:.:|....|
 Worm   328 GFLCKISSLTADRRTEWSKNRRKFFLNNAHNKKLLEVIETSQYVISMDTAKWG------------ 380

  Fly   368 TVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLE 432
              ....|:....| .:|:.|.|:     ||||||||...||.:|..|...|||.::|..:..:.|
 Worm   381 --VETSDKMSVYM-KDMLAGDGT-----NRWFDKTMNYAICANGRGGATGEHSPADGAEMDHVCE 437

  Fly   433 ---KIYKKIEEHPDEDNGL-------PQHHLPPPERLEWHVGPQLQLRFAQASKSVDKCIDDLDF 487
               .:.|:|.:.|.::..|       |.::|...|:||:.|...|:....:..::..|.:.||..
 Worm   438 NFLNLDKQILKSPSKEEQLEIAKLDEPSNYLKLAEKLEFEVEEGLEEEVERCYEAHTKAVADLHV 502

  Fly   488 YVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAASTE 552
            :...:..:||..:|.|.:|||.::|:|:|||:::..|:...|||:.|.|.:.:.|.:.:|..::.
 Worm   503 HSIIFLDFGKGRLKKCGISPDGFVQMAIQLAYFEDQGKFTQTYETGSIRFYANSRTETVRPVTSA 567

  Fly   553 ALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKN----IL 613
            :.:...||.              ||..|::.:         |:|.:.|    .||.|.|    :|
 Worm   568 SCKLVCAML--------------DETSSKQTR---------RQLLKEA----CEVHVNNCKEVML 605

  Fly   614 GNGIDIPL---------LGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVACSTDSFM---- 665
            |||.|..|         ||.....::             :..||.:|||||.:...|:|..
 Worm   606 GNGFDRHLFVLCVIAKGLGYNSPFLD-------------FFSSQKWLLSTSNIPNMTNSIAEDTS 657

  Fly   666 --------GYGPVTPRGYGCSY---NPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLL 719
                    .:|.|...|||..|   ..|  .|:..:::::|.|.|.:.|....|:.:...:..|.
 Worm   658 VNNIMLGGSFGAVAQDGYGICYRFGGNH--AILVHITSYHSSELTDSERIGNRLKSAFHRLAGLF 720

  Fly   720 QN 721
            .:
 Worm   721 DD 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	163/673 (24%)
cpt-3	NP_497498.2	Carn_acyltransf	128..716	CDD:376382	165/694 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920